Immunotherapy of cancer: regression of tumors after intralesional injection of living Mycobacterium bovis

Science. 1971 Apr 16;172(3980):271-3. doi: 10.1126/science.172.3980.271.

Abstract

Injection of living Mycobacterium bovis (strain BCG) into established intradermal tumors caused tumor regression and prevented the development of metastases.

MeSH terms

  • Animals
  • Carcinoma, Hepatocellular / therapy*
  • Disease Models, Animal
  • Guinea Pigs
  • Hypersensitivity, Delayed
  • Liver Neoplasms
  • Lymphatic Metastasis / prevention & control
  • Mycobacterium bovis / immunology*
  • Neoplasms, Experimental
  • Skin Neoplasms / therapy*