10 augustus: we hebben dit artikel naar voren gehaald omdat meer en meer duidelijk wordt dat veelvuldig mobiel bellen toch een zeker risico inhoudt voor met name het ontstaan van hersentumoren op langere termijn. Lees nog maar eens wat een bekend Japans neuroloog concludeert nadat hij meer dan 100 studies had bekeken. En onderaan een recente studie (juli 2009) toegevoegd die dan wel zegt dat er geen significant bewijs is maar toch ook opmerkt dat op langere termijn er wel een zeker risico is op het otnstaan van hersentumoren.

13 mei 2008 Bron: The independent Mobile phones 'more dangerous than smoking'

Een bekende Japanse neuroloog, Dr. Vini Kurana,  en expert op het gebied van hersentumoren voorspelt dat de mobiele telefoons op termijn voor een grote toename van kanker zal gaan zorgen. Dit meldt de Independent in Engeland. Deze arts en onderzoeker bekeek meer dan 100 studies en komt met deze alarmerende conclusie. In het artikel wordt ook gesteld dat bv. de franse regering kinderen aanraadt zo weinig mogelijk mobiel te bellen. Onder het artikel uit de Independent hebben we twee abstracten geplaatst van een Duitse studie, een Franse studie welke beide concluderen dat op korte termijn geen significant verschil werd gezien in een toename van hersentumoren door mobiel gebruik maar wel een toename op langere termijn (langer dan 10 jaar) voor mensen die veel mobiel bellen.
Brain expert warns of huge rise in tumours and calls on industry to take immediate steps to reduce radiation
By Geoffrey Lean
Sunday, 30 March 2008
Mobile phones could kill far more people than smoking or asbestos, a study by an award-winning cancer expert has concluded. He says people should avoid using them wherever possible and that governments and the mobile phone industry must take "immediate steps" to reduce exposure to their radiation.
The study, by Dr Vini Khurana, is the most devastating indictment yet published of the health risks.
It draws on growing evidence – exclusively reported in the IoS in October – that using handsets for 10 years or more can double the risk of brain cancer. Cancers take at least a decade to develop, invalidating official safety assurances based on earlier studies which included few, if any, people who had used the phones for that long.
Earlier this year, the French government warned against the use of mobile phones, especially by children. Germany also advises its people to minimise handset use, and the European Environment Agency has called for exposures to be reduced.
Professor Khurana – a top neurosurgeon who has received 14 awards over the past 16 years, has published more than three dozen scientific papers – reviewed more than 100 studies on the effects of mobile phones. He has put the results on a brain surgery website, and a paper based on the research is currently being peer-reviewed for publication in a scientific journal.
He admits that mobiles can save lives in emergencies, but concludes that "there is a significant and increasing body of evidence for a link between mobile phone usage and certain brain tumours". He believes this will be "definitively proven" in the next decade.
Noting that malignant brain tumours represent "a life-ending diagnosis", he adds: "We are currently experiencing a reactively unchecked and dangerous situation." He fears that "unless the industry and governments take immediate and decisive steps", the incidence of malignant brain tumours and associated death rate will be observed to rise globally within a decade from now, by which time it may be far too late to intervene medically.
"It is anticipated that this danger has far broader public health ramifications than asbestos and smoking," says Professor Khurana, who told the IoS his assessment is partly based on the fact that three billion people now use the phones worldwide, three times as many as smoke. Smoking kills some five million worldwide each year, and exposure to asbestos is responsible for as many deaths in Britain as road accidents.
Late last week, the Mobile Operators Association dismissed Khurana's study as "a selective discussion of scientific literature by one individual". It believes he "does not present a balanced analysis" of the published science, and "reaches opposite conclusions to the WHO and more than 30 other independent expert scientific reviews".
Hier een Duitse studie die stelt in hun abstract dat op korte termijn geen significant verschil werd gezien in een toename van hersentumoren door mobiel gebruik maar wel een toename op langere termijn (langer dan 10 jaar)
1: Am J Epidemiol. 2006 Mar 15;163(6):512-20. Epub 2006 Jan 27.Click here to read Links


Comment in:
Am J Epidemiol. 2006 Aug 1;164(3):294-5; author reply 295.
Cellular phones, cordless phones, and the risks of glioma and meningioma (Interphone Study Group, Germany).
Schüz J, Böhler E, Berg G, Schlehofer B, Hettinger I, Schlaefer K, Wahrendorf J, Kunna-Grass K, Blettner M.
Institute of Medical Biostatistics, Epidemiology and Informatics, Johannes Gutenberg-University of Mainz, Mainz, Germany. joachim@cancer.dk
The widespread use of cellular telephones has generated concern about possible adverse health effects, particularly brain tumors. In this population-based case-control study carried out in three regions of Germany, all incident cases of glioma and meningioma among patients aged 30-69 years were ascertained during 2000-2003. Controls matched on age, gender, and region were randomly drawn from population registries. In total, 366 glioma cases, 381 meningioma cases, and 1,494 controls were interviewed. Overall use of a cellular phone was not associated with brain tumor risk; the respective odds ratios were 0.98 (95% confidence interval (CI): 0.74, 1.29) for glioma and 0.84 (95% CI: 0.62, 1.13) for meningioma. Among persons who had used cellular phones for 10 or more years, increased risk was found for glioma (odds ratio = 2.20, 95% CI: 0.94, 5.11) but not for meningioma (odds ratio = 1.09, 95% CI: 0.35, 3.37). No excess of temporal glioma (p = 0.41) or meningioma (p = 0.43) was observed in cellular phone users as compared with nonusers. Cordless phone use was not related to either glioma risk or meningioma risk. In conclusion, no overall increased risk of glioma or meningioma was observed among these cellular phone users; however, for long-term cellular phone users, results need to be confirmed before firm conclusions can be drawn.
PMID: 16443797 [PubMed - indexed for MEDLINE]
1: Rev Epidemiol Sante Publique. 2007 Oct;55(5):321-32. Epub 2007 Sep 11.Click here to read Links
[Cell Phones and Risk of brain and acoustic nerve tumours: the French INTERPHONE case-control study]
[Article in French]

Hours M, Bernard M, Montestrucq L, Arslan M, Bergeret A, Deltour I, Cardis E.
Unité mixte de recherche épidémiologique et de surveillance transport travail environnement (INRETS/UCBL/InVS), faculté de médecine, domaine Rockefeller, 8, avenue Rockefeller, 69373 Lyon cedex 08, France. martine.hours@inrets.fr
BACKGROUND: Use of cell phones has increased dramatically since 1992 when they were first introduced in France. Certain electromagnetic fields (at extremely low frequency) have been recognized as possibly carcinogenic by the International Agency for Research on Cancer. Given the use of radiofrequency technology in cell phones, the rapid increase in the number of cell phones has generated concerns about the existence of a potential health hazard. To evaluate the relationship between the use of cell phones and the development of tumors of the head, a multicentric international study (INTERPHONE), coordinated by the International Agency for Research on Cancer, was carried out in 13 countries. This publication reports the results of the French part of the INTERPHONE study.
METHODS: INTERPHONE is a case-control study focused on tumors of the brain and central nervous system: gliomas, meningiomas and neuromas of cranial nerves. Eligible cases were men and women, residents of Paris or Lyon, aged 30-59, newly diagnosed with a first primary tumor between February 2001 and August 2003. The diagnoses were all either histologically confirmed or based upon unequivocal radiological images. Controls were matched for gender, age (+/-5 years) and place of residence. They were randomly drawn from electoral rolls. Detailed information was collected for all subjects during a computer-assisted face-to-face interview. Conditional logistic regression was used to estimate the odds ratio (OR) for an association between the use of cell phones and risk of each type of cancer.
RESULTS: Regular cell phone use was not associated with an increased risk of neuroma (OR=0,92; 95% confidence interval=[0.53-1.59]), meningioma (OR=0,74; 95% confidence interval=[0.43-1.28]) or glioma (OR=1.15; 95% confidence interval=[0.65-2.05]). Although these results are not statistically significant, a general tendency was observed for an increased risk of glioma among the heaviest users: long-term users, heavy users, users with the largest numbers of telephones.
CONCLUSION: No significant increased risk for glioma, meningioma or neuroma was observed among cell phone users participating in Interphone. The statistical power of the study is limited, however. Our results, suggesting the possibility of an increased risk among the heaviest users, therefore need to be verified in the international INTERPHONE analyses.
PMID: 17851009 [PubMed - indexed for MEDLINE]
1: Epidemiology. 2009 Jul 10. [Epub ahead of print] Links

Epidemiologic Evidence on Mobile Phones and Tumor Risk: A Review.
From the aDepartment of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; bEpidemiology and Public Health Unit, The Queensland Institute of Medical Research, Brisbane, Australia; cDepartment of Epidemiology, School of Public Health, University of California at Los Angeles, Los Angeles, CA; dEpidemiology, Biostatistics, and Disease Prevention Institute, Mount Sinai School of Medicine, New York, NY; and eSection of Epidemiology, Institute of Cancer Research, Sutton, Surrey, United Kingdom.
This review summarizes and interprets epidemiologic evidence bearing on a possible causal relation between radiofrequency field exposure from mobile phone use and tumor risk. In the last few years, epidemiologic evidence on mobile phone use and the risk of brain and other tumors of the head in adults has grown in volume, geographic diversity of study settings, and the amount of data on longer-term users. However, some key methodologic problems remain, particularly with regard to selective nonresponse and inaccuracy and bias in recall of phone use. Most studies of glioma show small increased or decreased risks among users, although a subset of studies show appreciably elevated risks. We considered methodologic features that might explain the deviant results, but found no clear explanation. Overall the studies published to date do not demonstrate an increased risk within approximately 10 years of use for any tumor of the brain or any other head tumor. Despite the methodologic shortcomings and the limited data on long latency and long-term use, the available data do not suggest a causal association between mobile phone use and fast-growing tumors such as malignant glioma in adults (at least for tumors with short induction periods). For slow-growing tumors such as meningioma and acoustic neuroma, as well as for glioma among long-term users, the absence of association reported thus far is less conclusive because the observation period has been too short.
PMID: 19593153 [PubMed - as supplied by publisher]
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