Rood vlees vergroot kans op darmkanker en spijsverteringskanker aldus grote epidemologische studie.

31 mei 2011: zie ook de nieuwste bevindingen van het WCRF over de relatie tussen leefstijl en voeding en het risico op (darm) kanker. Klik hier voor nieuwste studiegegevens

Actuele ontwikkelingen over therapeutische behandelingen van darmkankers zijn te lezen onder kankersoorten-darmkankers

12 januari 2005: Bron: Medisch tijdschrift JAMA

Grote epidemologische studie onder ca. 150.000 gezonde volwassenen in de leeftijd van 50 tot 74 jaar , gemiddelde leeftijd 63 jaar, toont aan dat veelvuldig gebruik van rood vlees en bewerkt vlees het risico op darmkanker en kanker van andere spijsverteringsorganen verhoogd. Voor vis en kip gold dat niet. Deze studie is uitgevoerd in periode 1982, 1992 en 2001. de resultaten uit deze studie zijn gepubliceerd in JAMA van 12 januari 2005 en bevestigen al eerder gedaan onderzoek naar risico op kanker van rood vlees en bewerkt vlees.

Meat Consumption and Risk of Colorectal Cancer Ann Chao, PhD; Michael J. Thun, MD, MS; Cari J. Connell, MPH; Marjorie L. McCullough, ScD; Eric J. Jacobs, PhD; W. Dana Flanders, MD, ScD; Carmen Rodriguez, MD, MPH; Rashmi Sinha, PhD; Eugenia E. Calle, PhD

JAMA. 2005;293:172-182.

Context Consumption of red and processed meat has been associated with colorectal cancer in many but not all epidemiological studies; few studies have examined risk in relation to long-term meat intake or the association of meat with rectal cancer.

Objective To examine the relationship between recent and long-term meat consumption and the risk of incident colon and rectal cancer.

Design, Setting, and Participants A cohort of 148 610 adults aged 50 to 74 years (median, 63 years), residing in 21 states with population-based cancer registries, who provided information on meat consumption in 1982 and again in 1992/1993 when enrolled in the Cancer Prevention Study II (CPS II) Nutrition Cohort. Follow-up from time of enrollment in 1992/1993 through August 31, 2001, identified 1667 incident colorectal cancers. Participants contributed person-years at risk until death or a diagnosis of colon or rectal cancer.

Main Outcome Measure Incidence rate ratio (RR) of colon and rectal cancer.

Results High intake of red and processed meat reported in 1992/1993 was associated with higher risk of colon cancer after adjusting for age and energy intake but not after further adjustment for body mass index, cigarette smoking, and other covariates. When long-term consumption was considered, persons in the highest tertile of consumption in both 1982 and 1992/1993 had higher risk of distal colon cancer associated with processed meat (RR, 1.50; 95% confidence interval , 1.04-2.17), and ratio of red meat to poultry and fish (RR, 1.53; 95% CI, 1.08-2.18) relative to those persons in the lowest tertile at both time points. Long-term consumption of poultry and fish was inversely associated with risk of both proximal and distal colon cancer. High consumption of red meat reported in 1992/1993 was associated with higher risk of rectal cancer (RR, 1.71; 95% CI, 1.15-2.52; P = .007 for trend), as was high consumption reported in both 1982 and 1992/1993 (RR, 1.43; 95% CI, 1.00-2.05).

Conclusions Our results demonstrate the potential value of examining long-term meat consumption in assessing cancer risk and strengthen the evidence that prolonged high consumption of red and processed meat may increase the risk of cancer in the distal portion of the large intestine.

Author Affiliations: Epidemiology and Surveillance Research, American Cancer Society (Drs Chao, Thun, McCullough, Jacobs, Flanders, Rodriguez, and Calle, and Ms Connell), and Department of Epidemiology, Rollins School of Public Health, Emory University (Dr Flanders), Atlanta, Ga; and Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Md (Dr Sinha).