Afgelopen week was er in Madrid ESMO 2023. Hier een aantal aanbevolen abstracten door vooraanstaande oncologen gerelateerd aan studies bij spijsverteringskanker waaronder vormen van darmkanker, alvleesklierkankerslokdarmkankerleverkanker en maagkanker.

De aanbevolen abstracten staan onder elkaar in dit artikel. Als u naar ESMO 2023  gaat kunt u via de nummers vooraf aan de titels van de abstracten deze vinden.

Aanbevolen abstracten door Dr. Elizabeth Smyth

Friday, October 20, 2023
14:00–15:40 CEST; Proffered Paper Session 1
Gastrointestinal Tumours, Upper Digestive 

LBA73 Pathological complete response (pCR) to durvalumab plus 5-fluorouracil, leucovorin, oxaliplatin and docetaxel (FLOT) in resectable gastric and gastroesophageal junction cancer (GC/GEJC): interim results of the global, Phase 3 MATTERHORN study. S-E Al-Batran

LBA74 Pembrolizumab plus chemotherapy vs chemotherapy as neoadjuvant and adjuvant therapy in locally-advanced gastric and gastroesophageal junction cancer: The Phase 3 KEYNOTE-585 study. K Shitara 

LBA75 Neoadjuvant chemoradiotherapy followed by surgery versus active surveillance for oesophageal cancer (SANO-trial): A phase-III stepped-wedge cluster randomised trial. BJ Van der Wilk 

1511O Pembrolizumab plus trastuzumab and chemotherapy for HER2+ metastatic gastric or gastroesophageal junction (mG/GEJ) adenocarcinoma: Survival results from the phase III, randomized, double-blind, placebo-controlled KEYNOTE-811 study. Yelena Y Janjigian 

Saturday, October 21, 2023
16:30–18:10 CEST; Mini Oral Session 1
Gastrointestinal Tumours, Upper Digestive

LBA78 Overall survival of perioperative or postoperative adjuvant oxaliplatin with S-1 versus adjuvant oxaliplatin with capecitabine in locally advanced gastric or gastro-oesophageal junction adenocarcinoma undergoing D2 gastrectomy: An updated analysis of RESOLVE trial. X Zhang

945MO AdvanTIG-206: Phase II randomized open-label study of ociperlimab (OCI) + tislelizumab (TIS) + BAT1706 (bevacizumab biosimilar) versus TIS + BAT1706 in patients (pts) with advanced hepatocellular carcinoma (HCC). MM Hou

1513MO A phase II study of nivolumab plus low dose ipilimumab as first -line therapy in patients with advanced gastric or esophago-gastric junction MSI-H tumor: First results of the NO LIMIT study (WJOG13320G/CA209-7W7). K Muro

Sunday, October 22, 2023
10:15–11:45 CEST; Proffered Paper Session
Gastrointestinal Tumours, Upper Digestive

LBA76 The primary results of an intergroup phase III randomized controlled trial comparing ramucirumab plus irinotecan with irinotecan in the third or later line treatment beyond progression after ramucirumab for advanced gastric cancer (RINDBeRG trial). S Kadowaki 

LBA77 5-fluorouracil and oxaliplatin with or without docetaxel in the first-line treatment of HER2 negative locally advanced (LA) unresectable or metastatic gastric or gastro-esophageal junction (GEJ) adenocarcinoma (GASTFOX-PRODIGE 51): A randomized phase III trial sponsored by the FFCD. A Zaanan 

LBA83 Neoadjuvant chemotherapy with FOLFIRINOX versus neoadjuvant gemcitabine-based chemoradiotherapy for borderline resectable and resectable pancreatic cancer (PREOPANC-2): A multicenter randomized controlled trial. BG Koerkamp 

1616O Nab-paclitaxel plus gemcitabine versus modified FOLFIRINOX or S-IROX in metastatic or recurrent pancreatic cancer (JCOG1611, GENERATE): A multicentred, randomized, open-label, three-arm, phase II/III trial. A Ohba





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