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19 september 2016: lees ook dit artikel:

5 april 2006: Bron: Chin J Integr Med. 2006 Mar;12(1):50-4.

Wanneer longkankerpatiënten die behandeld worden met chemo vooraf een injectie krijgen met Shenfu - Chinese kruiden - blijft de kwaliteit van leven van deze patiënten significant beter dan met alleen chemo. Dit blijkt uit een kleinschalige gerandomiseerde studie met 34 longkankerpatiënten met niet-klein-cellige longkanker.

Improvement of Quality of Life with Shenfu Injection in Non Small Cell Lung Cancer Patients Treated with Gemcitabine plus Cisplatin Regimen.

Wu WY, Long SQ, Zhang HB, Chai XS, Deng H, Xue XG, Wang B, Luo HY, Liu WS.
Department of Cancer, Guangdong Provincial Traditional Chinese Medicine Hospital, Guangzhou (510370). E-mail:

OBJECTIVE: To observe the effect of Shenfu injection (SFI) in treating non small cell lung cancer (NSCLC) patients on quality of life with gemcitabine (GEM) plus cisplatin (GP) regimen. METHODS: Thirty-four patients were ready to receive GP regimen chemotherapy for treating NSCLC disease, according to lot-drawing, they were divided into SFI pre-treatment group (18 cases) and SFI post-treatment group (16 cases). SFI pre-treatment group: During the first treatment course, chemotherapy was begun with SFI 60 ml, intravenous dripping on the 3rd day, once daily, consecutively for 10 days; on the 1st day, GP regimen (GEM 1250 mg/m(2), intravenous dripping, on the 1st and 8th day; cisplatin 70 mg/m(2) on the 2nd day; 21 days as one cycle) was carried out; in the second treatment course GP regimen was merely given to serve as the self-control. SFI post-treatment group: the medicament sequence order was reversed from that of pre-treatment group. Using dual international quality of life (QOL) scores, the effect of SFI on the patients' QOL was observed through randomized self pre- and post-crossover control.

RESULTS: The QOL in the 34 patients after being treated by SFI in combination with GP chemotherapy regimen in one group, and GP chemotherapy regimen alone in the other, was improved in different degrees, with significant difference (P < 0.01); comparision of SFI combined with GP chemotherapy regimen with GP chemotherapy alone showed that QOL in patients was significantly different (P < 0.01).

CONCLUSION: SFI could improve QOL in patients with NSCLC who were treated with GP regimen.

PMID: 16571285 [PubMed - in process]

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