24 juli 2025: The Lancet d.d. Online first July 23, 2025

Wie dagelijks 7000 stappen doet vermindert daarmee het risico op hart- en vaatziekten, kanker, dementie, diabetes en depressie. Alle Nederlandse media, zelfs het NOS journaal vermeldden deze uitkomsten van een grote meta-analyse van totaal 24 studies waarbij de nadruk lag op de 7000 stappen terwijl algemeen altijd is aangenomen dat 10.000 stappen nodig zouden zijn. Het verschil in totale sterfte tussen 2.000 en 7.000 stappen blijkt 47 procent te zijn gerekend over alles studies uit de meta-analyse.

"We hebben het idee dat we tienduizend stappen per dag moeten zetten, maar dat is niet gebaseerd op enig bewijs", zegt onderzoeksleider professor dr. Melody Ding. Bij de Olympische Spelen van 1964 werd een stappenteller uitgegeven die de tienduizendstappenteller werd genoemd. En vanaf toen zijn die 10.000 stappen een eigen leven gaan leiden. Maar aldus professor dr. Melody Ding: "Er zijn ook andere manieren om aan beweging te komen, zoals fietsen of zwemmen." Het belangrijkste is dat mensen bewust bezig zijn met beweging als onderdeel van een gezonde levensstijl.

Maar de studiepublicatie in the Lancet gaat over het aantal stappen dat dagelijks nodig zou zijn om het risico op hart- en vaatziekten, kanker, dementie, diabetes en depressie te verminderen.

Hier de vertaling van het abstract in het Nederlands wat de nadruk dus wel legt op het verschil tussen 7.000 en 10.000 stappen per dag met als basis een minimum van 2.000 stappen:

  • 57 studies uit 35 deelnemersgroepen werden opgenomen in de systematische review en 31 studies uit 24 groepen werden opgenomen in meta-analyses.
  • Voor totale mortaliteit, incidentie van hart- en vaatziekten, dementie en vallen werd een omgekeerd niet-lineair dosis-responsverband gevonden, met omslagpunten rond de 5000-7000 stappen per dag.
  • Een omgekeerd lineair verband werd gevonden voor mortaliteit door hart- en vaatziekten, incidentie van kanker, kankersterfte, incidentie van diabetes type 2 en depressieve symptomen.
  • Op basis van onze meta-analyses werd het aantal stappen per dag dat 7000 stappen per dag zette, vergeleken met 2000 stappen per dag, geassocieerd met een 47% lager risico op totale sterfte (HR 0,53 [95% BI 0,46–0,60]; I2=36,3; 14 studies),
  • een 25% lager risico op incidentie van hart- en vaatziekten (HR 0,75 [0,67–0,85]; I2=38,3%; zes studies),
  • een 47% lager risico op sterfte door hart- en vaatziekten (HR 0,53 [0,37–0,77]; I2=78,2%; drie studies),
  • een niet-significant 6% lager risico op incidentie van kanker (HR 0,94 [0,87–1,01]; I2=73,7%; twee studies),
  • een 37% lager risico op sterfte door kanker (HR 0,63 [0,55–0,72]; I2=64,5%; drie studies),
  • een 14% lager risico op diabetes type 2 (HR 0,86 [0,74–0,99]; I2=48,5%; vier studies),
  • een 38% lager risico op dementie (HR 0,62 [0,53–0,73]; I2=0%; twee studies),
  • een 22% lager risico op depressieve symptomen (HR 0,78 [0,73–0,83]; I2=36,2%; drie studies), en
  • een 28% lager risico op vallen (HR 0,72 [0,65–0,81]; I2=47,5%; vier studies).
  • Studies over fysieke functie (niet gebaseerd op meta-analyse) rapporteerden soortgelijke omgekeerde verbanden.
  • De bewijszekerheid was matig voor alle uitkomsten, behalve voor sterfte door hart- en vaatziekten (laag), incidentie van kanker (laag), fysieke functie (laag) en vallen (zeer laag).


Het volledige studierapport is gratis in gte zien of te downloaden:

Summary

Background

Despite the rapid increase in evidence from the past decade on daily steps and health-related outcomes, existing systematic reviews primarily focused on few outcomes, such as all-cause mortality. This study synthesised the prospective dose-response relationship between daily steps and health outcomes including all-cause mortality, cardiovascular disease, cancer, type 2 diabetes, cognitive outcomes, mental health outcomes, physical function, and falls.

Methods

For this systematic review and meta-analysis, we searched PubMed and EBSCO CINAHL for literature published between Jan 1, 2014, and Feb 14, 2025, supplemented by other search strategies. Eligible prospective studies examined the relationship between device-measured daily steps and health outcomes among adults without restrictions on language or publication type. Pairs of reviewers (BN, KO, ML, and TN) independently did the study selection, data extraction, and risk of bias assessment using the 9-point Newcastle-Ottawa Scale. Hazard ratios (HRs) from individual studies were synthesised using random-effects dose-response meta-analysis where possible. Certainty of evidence was assessed using GRADE. This trial is registered with PROSPERO (CRD42024529706).

Findings

57 studies from 35 cohorts were included in the systematic review and 31 studies from 24 cohorts were included in meta-analyses. For all-cause mortality, cardiovascular disease incidence, dementia, and falls, an inverse non-linear dose-response association was found, with inflection points at around 5000–7000 steps per day. An inverse linear association was found for cardiovascular disease mortality, cancer incidence, cancer mortality, type 2 diabetes incidence, and depressive symptoms. Based on our meta-analyses, compared with 2000 steps per day, 7000 steps per day was associated with a 47% lower risk of all-cause mortality (HR 0·53 [95% CI 0·46–0·60]; I2=36·3; 14 studies), a 25% lower risk of cardiovascular disease incidence (HR 0·75 [0·67–0·85]; I2=38·3%; six studies), a 47% lower risk of cardiovascular disease mortality (HR 0·53 [0·37–0·77]; I2=78·2%; three studies), a non-significant 6% lower risk of cancer incidence (HR 0·94 [0·87–1·01]; I2=73·7%; two studies), a 37% lower risk of cancer mortality (HR 0·63 [0·55–0·72]; I2=64·5%; three studies), a 14% lower risk of type 2 diabetes (HR 0·86 [0·74–0·99]; I2=48·5%; four studies), a 38% lower risk of dementia (HR 0·62 [0·53–0·73]; I2=0%; two studies), a 22% lower risk of depressive symptoms (HR 0·78 [0·73–0·83]; I2=36·2%; three studies), and a 28% lower risk of falls (HR 0·72 [0·65–0·81]; I2=47·5%; four studies). Studies on physical function (not based on meta-analysis) reported similar inverse associations. The evidence certainty was moderate for all outcomes except for cardiovascular disease mortality (low), cancer incidence (low), physical function (low), and falls (very low).

Interpretation

Although 10 000 steps per day can still be a viable target for those who are more active, 7000 steps per day is associated with clinically meaningful improvements in health outcomes and might be a more realistic and achievable target for some. The findings of the study should be interpreted in light of limitations, such as the small number of studies available for most outcomes, a lack of age-specific analysis and biases at the individual study level, including residual confounding.

Funding

National Health and Medical Research Council, New South Wales Health, and Ian Potter Foundation.

Figures (1)

Article metrics

Metric data currently unavailable

Supplementary material (1)


Research in context
Evidence before this study
Previous physical activity guidelines have considered step counts but found the evidence base insufficient for making recommendations. However, the past decade has seen a rapid advancement in the evidence surrounding step counts. In a systematic literature search done in December, 2024, without language restrictions across PubMed and EBSCO CINAHL, with search terms for step counts (eg, “daily steps” or “step counts”) in combination with specific terms for health outcomes (eg, “mortality” or “cancer”) and study type (eg, “meta-analysis” or “review”), complemented by Google Scholar and reference searches, we identified 13 systematic reviews addressing daily steps and health outcomes. All consistently found that higher daily step counts are associated with better health outcomes. However, most reviews focused on all-cause mortality and cardiovascular disease, leaving gaps in our understanding of the associations between step counts and other health outcomes, such as cancer and cognitive function.
Added value of this study
This study examines the prospective dose-response association between daily steps and a wide range of health outcomes, including all-cause mortality, cardiovascular disease incidence and mortality, type 2 diabetes incidence, cancer incidence and mortality, dementia, depressive symptoms, physical function, and falls. Our findings show consistent associations across all these outcomes despite variations in dose-response curves. Notably, a stepping volume of 7000 steps per day is associated with 6–47% lower risks compared with 2000 steps per day across all examined outcomes. However, the relationship between cadence (a proxy for stepping rate or intensity) and health outcomes remains less consistent.
Implications of all the available evidence
Daily steps should be considered a practical metric for physical activity guidelines and recommendations. The observed prospective dose-response relationship can inform step-based targets. Future research should account for potential dose-response variations by age, health outcome, device type, and measurement methods.

Contributors

DD, PC, and KO conceptualised the study. DD, BN, PCD, TN, ML, MEF, RD, UE, PC, and KO developed the review protocol. BN, TN, ML, and KO did the literature search and independently screened studies and extracted data. KO did all meta-analyses and PC provided advice on statistical analysis. DD drafted the paper. BdPC and BJJ did additional data analyses on primary studies and provided data or codes. ZM provided advice on certainty of evidence assessment. All authors provided critical input during the writing and revision of the paper, and all authors accept responsibility for the decision to submit the manuscript. DD attests that all listed authors meet authorship criteria and that no others meeting the criteria have been omitted. KO and PC have directly accessed and verified the data reported in the manuscript.

Data sharing

No additional data are available. Codes are available upon request.

Declaration of interests

We declare no competing interests.

Acknowledgments

We thank the following researchers for providing additional information or conducting additional analysis upon requests: Matthew Ahmadi (The University of Sydney); Jeffrey Annis (Vanderbilt University Medical Center); Marcel Ballin (Uppsala University); Lloyd Chan (University of New South Wales); Chutima Jalayondeja (Mahidol University); Aiden Doherty (University of Oxford); Kosuke Inoue (Kyoto University); Asier Mañas (the University of Castilla–La Mancha); Alaina Shreves (University of Oxford); and Scott Small (University of Oxford). We also thank Jessica Bellamy and Laura Smith from the University of Wollongong for their help with literature searches. This study was funded by an Investigator Grant from the Australian National Health and Medical Research Council (2009254 to DD; 2025541 to CS; 1142685 to PCD; 1176858 to AK), an Early-Mid Career Researcher Grant from the NSW Ministry of Health (DD), and a Public Health Grant from Ian Potter Foundation (DD). The funders had no role in any phase of the study. This work was part of an evidence review completed for an update of the Australian 24h movement guidelines for adults and older adults, funded by contract research awarded to the University of Wollongong by the Australian Government Department of Health and Aged Care.

Supplementary Material (1)

Supplementary appendix

References

WHO
WHO guidelines on physical activity and sedentary behaviour
World Health Organization, 2020
Katzmarzyk, PT ∙ Friedenreich, C ∙ Shiroma, EJ ∙ et al.
Physical inactivity and non-communicable disease burden in low-income, middle-income and high-income countries
Br J Sports Med. 2022; 56:101-106
Ding, D ∙ Lawson, KD ∙ Kolbe-Alexander, TL ∙ et al.
The economic burden of physical inactivity: a global analysis of major non-communicable diseases
Lancet. 2016; 388:1311-1324
Strain, T ∙ Flaxman, S ∙ Guthold, R ∙ et al.
National, regional, and global trends in insufficient physical activity among adults from 2000 to 2022: a pooled analysis of 507 population-based surveys with 5·7 million participants
Lancet Glob Health. 2024; 12:e1232-e1243
Ding, D ∙ Mutrie, N ∙ Bauman, A ∙ et al.
Physical activity guidelines 2020: comprehensive and inclusive recommendations to activate populations
Lancet. 2020; 396:1780-1782
US Department of Health and Human Services
Physical activity guidelines for Americans
US Department of Health and Human Services, 2018
Bassett, Jr, DR ∙ Toth, LP ∙ LaMunion, SR ∙ et al.
Step counting: a review of measurement considerations and health-related applications
Sports Med. 2017; 47:1303-1315
Tudor-Locke, C ∙ Bassett, Jr, DR
How many steps/day are enough? Preliminary pedometer indices for public health
Sports Med. 2004; 34:1-8
Stamatakis, E ∙ Ahmadi, M ∙ Murphy, MH ∙ et al.
Journey of a thousand miles: from ‘Manpo-Kei’ to the first steps-based physical activity recommendations
Br J Sports Med. 2023; 57:1227-1228
Kraus, WE ∙ Janz, KF ∙ Powell, KE ∙ et al.
Daily step counts for measuring physical activity exposure and its relation to health
Med Sci Sports Exerc. 2019; 51:1206-1212
Banach, M ∙ Lewek, J ∙ Surma, S ∙ et al.
The association between daily step count and all-cause and cardiovascular mortality: a meta-analysis
Eur J Prev Cardiol. 2023; 30:1975-1985
Hall, KS ∙ Hyde, ET ∙ Bassett, DR ∙ et al.
Systematic review of the prospective association of daily step counts with risk of mortality, cardiovascular disease, and dysglycemia
Int J Behav Nutr Phys Act. 2020; 17:78
Jayedi, A ∙ Gohari, A ∙ Shab-Bidar, S
Daily step count and all-cause mortality: a dose-response meta-analysis of prospective cohort studies
Sports Med. 2022; 52:89-99
Liew, SJ ∙ Petrunoff, NA ∙ Neelakantan, N ∙ et al.
Device-measured physical activity and sedentary behavior in relation to cardiovascular diseases and all-cause mortality: systematic review and meta-analysis of prospective cohort studies
AJPM Focus. 2022; 2, 100054
Liu, Y ∙ Sun, Z ∙ Wang, X ∙ et al.
Dose-response association between the daily step count and all-cause mortality: a systematic review and meta-analysis
J Sports Sci. 2022; 40:1678-1687
Paluch, AE ∙ Bajpai, S ∙ Bassett, DR ∙ et al.
Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts
Lancet Public Health. 2022; 7:e219-e228
Stens, NA ∙ Bakker, EA ∙ Mañas, A ∙ et al.
Relationship of daily step counts to all-cause mortality and cardiovascular events
J Am Coll Cardiol. 2023; 82:1483-1494
Isath, A ∙ Virani, SS ∙ Wang, Z ∙ et al.
Meta-analysis of per-day step count and all-cause mortality
Am J Cardiol. 2022; 180:166-168
The Department of Health Australian Government
Australia's physical activity and sedentary behaviour guidelines
Paluch, AE ∙ Bajpai, S ∙ Ballin, M ∙ et al.
Prospective association of daily steps with cardiovascular disease: a harmonized meta-analysis
Circulation. 2023; 147:122-131
Rojer, AGM ∙ Ramsey, KA ∙ Amaral Gomes, ES ∙ et al.
Objectively assessed physical activity and sedentary behavior and global cognitive function in older adults: a systematic review
Mech Ageing Dev. 2021; 198, 111524
Del Pozo Cruz, B ∙ Gallardo-Gomez, D ∙ Del Pozo-Cruz, J ∙ et al.
How many steps a day to reduce the risk of all-cause mortality? A dose-response meta-analysis
J Intern Med. 2022; 291:519-521
Sheng, M ∙ Yang, J ∙ Bao, M ∙ et al.
The relationships between step count and all-cause mortality and cardiovascular events: a dose-response meta-analysis
J Sport Health Sci. 2021; 10:620-628
Rosmaninho, I ∙ Ribeirinho-Soares, P ∙ Nunes, JPL
Walking speed and mortality: an updated systematic review
South Med J. 2021; 114:697-702
Paluch, AE ∙ Gabriel, KP ∙ Fulton, JE ∙ et al.
Steps per day and all-cause mortality in middle-aged adults in the coronary artery risk development in young adults study
JAMA Netw Open. 2021; 4, e2124516
Del Pozo Cruz, B ∙ Ahmadi, M ∙ Naismith, SL ∙ et al.
Association of daily step count and intensity with incident dementia in 78 430 adults living in the UK
JAMA Neurol. 2022; 79:1059-1063
Del Pozo Cruz, B ∙ Ahmadi, MN ∙ Lee, IM ∙ et al.
Prospective associations of daily step counts and intensity with cancer and cardiovascular disease incidence and mortality and all-cause mortality
JAMA Intern Med. 2022; 182:1139-1148
Mañas, A ∙ Del Pozo Cruz, B ∙ Ekelund, U ∙ et al.
Association of accelerometer-derived step volume and intensity with hospitalizations and mortality in older adults: A prospective cohort study
J Sport Health Sci. 2022; 11:578-585
Chan, LLY ∙ van Schooten, KS ∙ Lord, SR ∙ et al.
Short daily-life walking bouts and poor self-reported health predict the onset of depression in community-dwelling older people: a 2-year longitudinal cohort study
J Am Med Dir Assoc. 2022; 23:1242-1247
Saint-Maurice, PF ∙ Troiano, RP ∙ Bassett, Jr, DR ∙ et al.
Association of Daily step count and step intensity with mortality among US adults
JAMA. 2020; 323:1151-1160
Lee, IM ∙ Shiroma, EJ ∙ Kamada, M ∙ et al.
Association of step volume and intensity with all-cause mortality in older women
JAMA Intern Med. 2019; 179:1105-1112
Cochrane, SK ∙ Chen, SH ∙ Fitzgerald, JD ∙ et al.
Association of accelerometry-measured physical activity and cardiovascular events in mobility-limited older adults: the LIFE (Lifestyle Interventions and Independence for Elders) study
J Am Heart Assoc. 2017; 6, e007215
Cuthbertson, CC ∙ Evenson, KR ∙ Wen, F ∙ et al.
Associations of steps per day and step intensity with the risk of cancer: findings from the Women's Health Accelerometry Collaboration cohort
Prev Med. 2024; 186, 108070
Shreves, AH ∙ Small, SR ∙ Walmsley, R ∙ et al.
Amount and intensity of physical activity and risk of incident cancer in the UK Biobank
medRxiv. 2023;
Cuthbertson, CC ∙ Moore, CC ∙ Sotres-Alvarez, D ∙ et al.
Associations of steps per day and step intensity with the risk of diabetes: the Hispanic Community Health Study / Study of Latinos (HCHS/SOL)
Int J Behav Nutr Phys Act. 2022; 19:46
Garduno, AC ∙ LaCroix, AZ ∙ LaMonte, MJ ∙ et al.
Associations of Daily steps and step intensity with incident diabetes in a prospective cohort study of older women: the OPACH study
Diabetes Care. 2022; 45:339-347
Chan, LLY ∙ Arbona, CH ∙ Brodie, MA ∙ et al.
Prediction of injurious falls in older adults using digital gait biomarkers extracted from large-scale wrist sensor data
Age Ageing. 2023; 52, afad179
Tudor-Locke, C ∙ Han, H ∙ Aguiar, EJ ∙ et al.
How fast is fast enough? Walking cadence (steps/min) as a practical estimate of intensity in adults: a narrative review
Br J Sports Med. 2018; 52:776-788
Tateuchi, H ∙ Akiyama, H ∙ Goto, K ∙ et al.
Gait- and posture-related factors associated with changes in hip pain and physical function in patients with secondary hip osteoarthritis: a prospective cohort study
Arch Phys Med Rehabil. 2019; 100:2053-2062
Wells, GA ∙ Shea, B ∙ O'Connell, D ∙ et al.
The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses
https://www.ohri.ca/programs/clinical_epidemiology/oxford.asp
Date: 2013
Date accessed: July 10, 2025
Ramsey, CM ∙ Lynch, KG ∙ Gehrman, PR ∙ et al.
Daily steps and depressive symptoms: a longitudinal evaluation of patients with major depressive disorder in the precision medicine in mental health care study
J Affect Disord. 2022; 300:334-340
Shibukawa, T ∙ Fujiyoshi, A ∙ Moniruzzaman, M ∙ et al.
Association of step counts with cognitive function in apparently healthy middle-aged and older Japanese men
Prev Med Rep. 2024; 38, 102615
Ahmadi, MN ∙ Rezende, LFM ∙ Ferrari, G ∙ et al.
Do the associations of daily steps with mortality and incident cardiovascular disease differ by sedentary time levels? A device-based cohort study
Br J Sports Med. 2024; 58:261-268
Ballin, M ∙ Nordström, P ∙ Niklasson, J ∙ et al.
Daily step count and incident diabetes in community-dwelling 70-year-olds: a prospective cohort study
BMC Public Health. 2020; 20, 1830
Inoue, K ∙ Tsugawa, Y ∙ Mayeda, ER ∙ et al.
Association of daily step patterns with mortality in US adults
JAMA Netw Open. 2023; 6, e235174
Jefferis, BJ ∙ Merom, D ∙ Sartini, C ∙ et al.
Physical activity and falls in older men: the critical role of mobility limitations
Med Sci Sports Exerc. 2015; 47:2119-2128
Master, H ∙ Annis, J ∙ Huang, S ∙ et al.
Association of step counts over time with the risk of chronic disease in the All of Us Research Program
Nat Med. 2022; 28:2301-2308
Perry, AS ∙ Annis, JS ∙ Master, H ∙ et al.
Association of longitudinal activity measures and diabetes risk: an analysis from the National Institutes of Health All of Us Research Program
J Clin Endocrinol Metab. 2023; 108:1101-1109
Aranyavalai, T ∙ Jalayondeja, C ∙ Jalayondeja, W ∙ et al.
Association between walking 5000 step/day and fall incidence over six months in urban community-dwelling older people
BMC Geriatr. 2020; 20:194
Small, SR ∙ Chan, S ∙ Walmsley, R ∙ et al.
Self-supervised machine learning to characterize step counts from wrist-worn accelerometers in the UK Biobank
Med Sci Sports Exerc. 2024; 56:1945-1953
Chan, LLY ∙ Brodie, MA ∙ Lord, SR
Prediction of incident depression in middle-aged and older adults using digital gait biomarkers extracted from large-scale wrist sensor data
J Am Med Dir Assoc. 2023; 24:1106-1113
Deeks, JJ ∙ Higgins, JPT ∙ Altman, DG
Chapter 10: analysing data and undertaking meta-analyses
Higgins, JPT ∙ Thomas, J ∙ Chandler, J ∙ et al. (Editors)
Cochrane Handbook for Systematic Reviews of Interventions version 6.2
Cochrane, 2021
Higgins, JPT ∙ Li, T ∙ Deeks, JJ
Chapter 6: choosing effect measures and computing estimates of effect
Higgins, JPT ∙ Thomas, J ∙ Chandler, J ∙ et al. (Editors)
Cochrane Handbook for Systematic Reviews of Interventions version 6.1
Cochrane, 2020
VanderWeele, TJ
Optimal approximate conversions of odds ratios and hazard ratios to risk ratios
Biometrics. 2020; 76:746-752
Crippa, A ∙ Discacciati, A ∙ Bottai, M ∙ et al.
One-stage dose-response meta-analysis for aggregated data
Stat Methods Med Res. 2019; 28:1579-1596
Orsini, N ∙ Li, R ∙ Wolk, A ∙ et al.
Meta-analysis for linear and nonlinear dose-response relations: examples, an evaluation of approximations, and software
Am J Epidemiol. 2012; 175:66-73
DerSimonian, R ∙ Laird, N
Meta-analysis in clinical trials
Control Clin Trials. 1986; 7:177-188
Tudor-Locke, C ∙ Craig, CL ∙ Aoyagi, Y ∙ et al.
How many steps/day are enough? For older adults and special populations
Int J Behav Nutr Phys Act. 2011; 8:80
Sera, F ∙ Armstrong, B ∙ Blangiardo, M ∙ et al.
An extended mixed-effects framework for meta-analysis
Stat Med. 2019; 38:5429-5444
Gasparrini, A
SF, & Gasparrini M. A. Package ‘mixmeta’
https://cran.r-project.org/web/packages/mixmeta/mixmeta.pdf
Date: Oct 13, 2021
Date accessed: July 10, 2025
Guyatt, G ∙ Oxman, AD ∙ Akl, EA ∙ et al.
GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables
J Clin Epidemiol. 2011; 64:383-394
Murad, MH ∙ Verbeek, J ∙ Schwingshackl, L ∙ et al.
GRADE GUIDANCE 38: updated guidance for rating up certainty of evidence due to a dose-response gradient
J Clin Epidemiol. 2023; 164:45-53
Sterne, JAC ∙ Egger, M ∙ Moher, D
Chapter 10: addressing reporting biases
Higgins, JPT ∙ Green, S (Editors)
Cochrane Handbook for Systematic Reviews of Intervention version 5.1
Cochrane, 2011
Egger, M ∙ Davey Smith, G ∙ Schneider, M ∙ et al.
Bias in meta-analysis detected by a simple, graphical test
BMJ. 1997; 315:629-634
Page, MJ ∙ Higgins, JPT ∙ Sterne, JAC
Chapter 13: assessing risk of bias due to missing results in a synthesis
Higgins, JPT ∙ Thomas, J ∙ Chandler, J ∙ et al. (Editors)
Cochrane Handbook for Systematic Reviews of Interventions version 6
Cochrane, 2019
de Paula, D ∙ Evenson, KR ∙ Feter, N ∙ et al.
Daily steps, activity, sedentary and sleep behaviors associations with all-cause mortality: the ELSA-Brasil study
Prev Med. 2025; 192, 108241
Dwyer, T ∙ Pezic, A ∙ Sun, C ∙ et al.
Objectively measured daily steps and subsequent long term all-cause mortality: the tasped prospective cohort study
PLoS One. 2015; 10, e0141274
Fox, KR ∙ Ku, PW ∙ Hillsdon, M ∙ et al.
Objectively assessed physical activity and lower limb function and prospective associations with mortality and newly diagnosed disease in UK older adults: an OPAL four-year follow-up study
Age Ageing. 2015; 44:261-268
Fretts, AM ∙ Siscovick, DS ∙ Malloy, K ∙ et al.
Ambulatory activity and risk of premature mortality among young and middle-aged American Indian individuals
JAMA Netw Open. 2023; 6, e2311476
Hamaya, R ∙ Shiroma, Jr, EJ ∙ Moore, CC ∙ et al.
Time- vs step-based physical activity metrics for health
JAMA Intern Med. 2024; 184:718-725
Hansen, BH ∙ Dalene, KE ∙ Ekelund, U ∙ et al.
Step by step: Association of device-measured daily steps with all-cause mortality: a prospective cohort study
Scand J Med Sci Sports. 2020; 30:1705-1711
Jefferis, BJ ∙ Parsons, TJ ∙ Sartini, C ∙ et al.
Objectively measured physical activity, sedentary behaviour and all-cause mortality in older men: does volume of activity matter more than pattern of accumulation?
Br J Sports Med. 2019; 53:1013-1020
Oftedal, S ∙ Holliday, EG ∙ Attia, J ∙ et al.
Daily steps and diet, but not sleep, are related to mortality in older Australians
J Sci Med Sport. 2020; 23:276-282
Watanabe, D ∙ Yoshida, T ∙ Watanabe, Y ∙ et al.
Dose-response relationships between objectively measured daily steps and mortality among frail and nonfrail older adults
Med Sci Sports Exerc. 2023; 55:1044-1053
Yamamoto, N ∙ Miyazaki, H ∙ Shimada, M ∙ et al.
Daily step count and all-cause mortality in a sample of Japanese elderly people: a cohort study
BMC Public Health. 2018; 18:540
Cavalheri, V ∙ Grigoletto, I ∙ McVeigh, J ∙ et al.
Association between physical activity and reduced mortality in inoperable lung cancer
J Clin Med. 2023; 12, 7346
Del Pozo-Cruz, J ∙ Alvarez-Barbosa, F ∙ Gallardo-Gomez, D ∙ et al.
Optimal number of steps per day to prevent all-cause mortality in people with prediabetes and diabetes
Diabetes Care. 2022; 45:2156-2158
Schneider, CV ∙ Zandvakili, I ∙ Thaiss, CA ∙ et al.
Physical activity is associated with reduced risk of liver disease in the prospective UK Biobank cohort
JHEP Rep Innov Hepatol. 2021; 3, 100263
Watanabe, D ∙ Yoshida, T ∙ Watanabe, Y ∙ et al.
Association between doubly labelled water-calibrated energy intake and objectively measured physical activity with mortality risk in older adults
Int J Behav Nutr Phys Act. 2023; 20:150
Zhou, Y ∙ Sun, X ∙ Yang, G ∙ et al.
Sex-specific differences in the association between steps per day and all-cause mortality among a cohort of adult patients from the United States with congestive heart failure
Heart Lung. 2023; 62:175-179
Shimoda, T ∙ Tomida, K ∙ Nakajima, C ∙ et al.
Dose-response relationships of daily steps with disability incidence and all-cause mortality stratified by age and physical frailty
J Am Med Dir Assoc. 2025; 26, 105356
Guo, T ∙ Zhou, Y ∙ Yang, G ∙ et al.
Associations of daily step count with all-cause mortality and cardiovascular mortality in hypertensive US adults: a cohort study from NHANES 2005–2006
BMC Public Health. 2025; 25:129
Jefferis, BJ ∙ Parsons, TJ ∙ Sartini, C ∙ et al.
Does total volume of physical activity matter more than pattern for onset of CVD? A prospective cohort study of older British men
Int J Cardiol. 2019; 278:267-272
LaMonte, MJ ∙ LaCroix, AZ ∙ Nguyen, S ∙ et al.
Accelerometer-measured physical activity, sedentary time, and heart failure risk in women aged 63 to 99 years
JAMA Cardiol. 2024; 9:336-345
Moniruzzaman, M ∙ Kadota, A ∙ Segawa, H ∙ et al.
Relationship between step counts and cerebral small vessel disease in Japanese men
Stroke. 2020; 51:3584-3591
Pan, S ∙ Chen, S ∙ Fretts, AM ∙ et al.
Associations of pedometer-measured ambulatory activity with incidence of atherosclerotic cardiovascular diseases: strong heart family study
Prev Med. 2023; 177, 107781
Yates, T ∙ Haffner, SM ∙ Schulte, PJ ∙ et al.
Association between change in daily ambulatory activity and cardiovascular events in people with impaired glucose tolerance (NAVIGATOR trial): a cohort analysis
Lancet. 2014; 383:1059-1066
Kraus, WE ∙ Yates, T ∙ Tuomilehto, J ∙ et al.
Relationship between baseline physical activity assessed by pedometer count and new-onset diabetes in the NAVIGATOR trial
BMJ Open Diabetes Res Care. 2018; 6, e000523
Nguyen, S ∙ LaCroix, AZ ∙ Hayden, KM ∙ et al.
Accelerometer-measured physical activity and sitting with incident mild cognitive impairment or probable dementia among older women
Alzheimers Dement. 2023; 19:3041-3054
Chen, ST ∙ Stevinson, C ∙ Tian, T ∙ et al.
Accelerometer-measured daily steps and subjective cognitive ability in older adults: a two-year follow-up study
Exp Gerontol. 2020; 133, 110874
Raudsepp, L ∙ Riso, EM
Longitudinal association between objectively measured walking and depressive symptoms among Estonian older adults
J Aging Phys Act. 2017; 25:639-645
Hsueh, MC ∙ Stubbs, B ∙ Lai, YJ ∙ et al.
A dose response relationship between accelerometer assessed daily steps and depressive symptoms in older adults: a two-year cohort study
Age Ageing. 2021; 50:519-526
Hsueh, MC ∙ Lin, CY ∙ Lai, TF ∙ et al.
Is achieving 7,000 steps/day cross-sectionally and prospectively associated with older adults' lower-extremity performance?
BMC Geriatr. 2021; 21:359
Makino, K ∙ Lee, S ∙ Lee, S ∙ et al.
Daily physical activity and functional disability incidence in community-dwelling older adults with chronic pain: a prospective cohort study
Pain Med. 2019; 20:1702-1710
Taylor, NF ∙ Peiris, CL ∙ Thompson, AL ∙ et al.
Association between physical activity and short-term physical function changes after hip fracture: an observational study
Physiother Res Int. 2021; 26, e1876
White, DK ∙ Tudor-Locke, C ∙ Zhang, Y ∙ et al.
Daily walking and the risk of incident functional limitation in knee osteoarthritis: an observational study
Arthritis Care Res (Hoboken). 2014; 66:1328-1336
Schumacher, BT ∙ Bellettiere, J ∙ LaMonte, MJ ∙ et al.
Accelerometer-measured daily steps, physical function, and subsequent fall risk in older women: the objective physical activity and cardiovascular disease in older women study
J Aging Phys Act. 2021; 30:635-645
Martinez-Gomez, D ∙ Luo, M ∙ Huang, Y ∙ et al.
Physical activity and all-cause mortality by age in 4 multinational megacohorts
JAMA Netw Open. 2024; 7, e2446802
Nakagata, T ∙ Murakami, H ∙ Kawakami, R ∙ et al.
Step-count outcomes of 13 different activity trackers: results from laboratory and free-living experiments
Gait Posture. 2022; 98:24-33
Fry, A ∙ Littlejohns, TJ ∙ Sudlow, C ∙ et al.
Comparison of sociodemographic and health-related characteristics of UK Biobank participants with those of the general population
Am J Epidemiol. 2017; 186:1026-1034
Ding, D ∙ Tarp, J ∙ Giovannucci, E ∙ et al.
Causal inference in physical activity epidemiology research: an opportunity for better evidence
Br J Sports Med. 2025;
Treacy, D ∙ Hassett, L ∙ Schurr, K ∙ et al.
Validity of different activity monitors to count steps in an inpatient rehabilitation setting
Phys Ther. 2017; 97:581-588

Related Specialty Collections

This article can be found in the following collections:

Plaats een reactie ...

Reageer op "Dagelijks 7.000 stappen / wandelen vermindert het risico op hart- en vaatziekten, kanker, dementie, diabetes en depressie aantoonbaar"


Gerelateerde artikelen
 

Gerelateerde artikelen

Dagelijks 7.000 stappen / >> Fysiek actieve mensen hebben >> Intensieve lichaamsbeweging >> Korte stevige wandeling elke >> Lichaamsbeweging kan hartaanvallen >> uurtje joggen per week voorkomt >> Bewegen en risico op kanker: >> Bewegen en sporten: Lichamelijk >> Bewegen: Mensen die te weinig >>