Helpt u ons aan 500 donateurs?

19 mei 2018: lees ook dit artikel: 

https://kanker-actueel.nl/ivo-visser-uitbehandeld-voor-zeldzame-vorm-van-lymfklierkanker-komt-alsnog-in-total-remissie-kankervrij-met-t-car-cel-immuuntherapie.html

31 augustus 2017: Lees ook dit artikel: 

https://kanker-actueel.nl/NL/immuuntherapie-met-car-t-cell-therapy-tisagenlecleucel-kymriah-goedgekeurd-door-fda-voor-gebruik-bij-kinderen-en-jong-volwassenen-met-vorm-van-acute-lymfatische-leukemie-all.html

7 november 2015: lees het verhaal van Layla, een baby nog geen jaar oud die via immuuntherapie met T-cellen van een donor, T-cell enginering geheten, toegepast vlak voordat ze zou sterven, alsnog in een totale remissie kwam en nu al ruim dire maanden kankervrij is. Het verhaal van Layla met All - Acute Lymfatische Leukemie is wereldwijd overal gepubliceerd maar lees hier hoe de Volkskrant en Nature erover schrijven: 

https://kanker-actueel.nl/NL/layla-een-baby-met-ongeneeslijke-vorm-van-all-acute-lymfatische-leukemie-lijkt-alsnog-te-genezen-door-immuuntherapie-met-t-cellen-van-een-donor-via-t-cell-enginering-therapie.html

28 november 2016: kijk naar Nieuwsuur: http://nos.nl/nieuwsuur/artikel/2145326-vaccin-tegen-huidkanker-voor-meer-mensen-beschikbaar.html?title=vaccin-tegen-huidkanker-voor-meer-mensen-beschikbaar

en in het NPO journaal d.d. 28 november 2016: http://www.npo.nl/live/npo-1

het item met Jolanda de Vries over immuuntherapie met dendritische celtherapie bij melanomen, wat wel wat anders gaat dan met T-CAR cells (TIL - Tumor Infiltrating Lymfocyten) zoals hieronder beschreven maar is wel heel interessant. joalanda was ook bij ons overleg over utopie of uitdaging afgelopen woensdag 23 november 2016

TIL - tumor infiltrating lymfocytes werkingsmechanisme

31 maart 2016: Bron: VWS

Gaat het dan nu eindelijk gebeuren? Het is nog maar een heel klein begin maar wel hoopgevend dat Minister Schippers dendritische celtherapie met T-CAR cells (TIL - Tumor Infiltrating Lymfocyten) bij melanomen in stadium IIIB en IIIC als proef gaat vergoeden vanuit het basispakket per 1 april 2016.

Het is een heel bescheiden begin want als je dit studierapport leest:  CAR-modified T-cell therapy for cancer: an updated review met een update van dendritische celtherapie met TIL - Tumor Infiltrating Lymfocyten bij veel verschillende vormen van kanker dan zou deze vorm van behandelen toch al lang moeten worden toegepast als studie in een veel eerder stadium van de ziekte en bij nagenoeg elke vorm van kanker lijkt mij.  Want eigenljk altijd zijn de resultaten positief en dat bij vaak zwaar voorbehandelede kankerpatiënten. Zie ook referentielijst onderaan dit artikel

T-car cells

Zie ook deze artikelen over immuuntherapie met TIL - tumor infiltrating Lymfocyten:

https://kanker-actueel.nl/NL/immuuntherapie-met-til-tumor-infiltrating-lymfocyten-zorgt-bij-een-kwart-van-de-deelnemers-voor-jarenlange-ziektevrije-tijd-bij-patienten-met-uitgezaaide-melanomen-copy-1.html

en TILL bij Acute Lymfatische Leukemie - ALL: 

https://kanker-actueel.nl/NL/receptor-gemodificeerde-t-cellen-leiden-tot-totale-remissies-bij-uitbehandelde-agressieve-acute-lymfatische-leukemie-all-en-geven-hoop-op-genezende-behandeling-copy-1.html

en TILL bij bepaalde vorm van leukemie en lymfklierkanker: 

https://kanker-actueel.nl/NL/immuuntherapie-met-gemanipuleerde-t-cellen-geeft-spectaculair-goede-resultaten-bij-vormen-van-patienten-met-vergevorderde-leukemie-en-b-cel-lymfomen.html

Dit persbericht ontving ik vanmorgen in mijn mailbox:

Immuuntherapie tegen huidkanker voorwaardelijk toegelaten tot het basispakket

Minister Edith Schippers (VWS) laat de huidkankerbehandeling Dendritische Celtherapie voorwaardelijk toe tot het basispakket van de zorgverzekering. De vergoeding gaat in op 1 april 2016. Dat schrijft zij vandaag in een brief aan de Tweede Kamer.

Celtherapie

Dendritische celtherapie is een experimentele behandeling waarbij de patiënt een vaccin krijgt toegediend dat zijn immuunsysteem stimuleert om kankercellen op te ruimen.

Vergoeding

De vergoeding van dendritische celtherapie geldt voor de duur van vijf jaar en vier maanden. De therapie wordt vergoed voor patiënten met stadium IIIB en IIIC melanoom (specifieke vorm van huidkanker) na complete resectie (medische uitsnijding). Voor deze voorwaardelijke toelating is een budget van 19,9 miljoen euro beschikbaar.

Voorwaardelijke toelating

In 2012 werd voor het eerst een behandeling voorwaardelijk toegelaten. Door behandelingen en medicijnen voorwaardelijk tot het verzekerde pakket toe te laten krijgen patiënten toegang tot deze veelbelovende vormen van zorg en komt er inzicht in de effectiviteit en kosteneffectiviteit van deze zorg. Na afloop van de periode van voorwaardelijke toelating wordt besloten over daadwerkelijke toelating tot het verzekerde pakket.

Mocht u kanker-actueel de moeite waard vinden en ons willen ondersteunen om kanker-actueel online te houden dan kunt u ons machtigen voor een periodieke donatie via donaties: https://kanker-actueel.nl/NL/donaties.html of doneer al of niet anoniem op - rekeningnummer NL79 RABO 0372931138 t.n.v. Stichting Gezondheid Actueel in Amersfoort. Onze IBANcode is NL79 RABO 0372 9311 38   
Elk bedrag is welkom. En we zijn een ANBI instelling dus uw donatie of gift is in principe aftrekbaar voor de belasting.

En als donateur kunt u ook korting krijgen bij verschillende bedrijven: 

https://kanker-actueel.nl/NL/voordelen-van-ops-lidmaatschap-op-een-rijtje-gezet-inclusief-hoe-het-kookboek-en-de-recepten-op-basis-van-uitgangspunten-van-houtsmullerdieet-te-downloaden-enof-in-te-zien.html

This review outlines four generations of CAR. The pre-clinical and clinical studies showed that this technique has a great potential for treatment of solid and hematological malignancies. The main purpose of the current review is to focus on the pre-clinical and clinical developments of CAR-based immunotherapy

Review

CAR-modified T-cell therapy for cancer: an updated review

Full text HTML
Free access
DOI:
10.3109/21691401.2015.1052465
Mostafa Haji-Fatahalihaabc, Maryam Hosseinibc, Asiye Akbariand, Sanam Sadreddiniabc, Farhad Jadidi-Niaraghe & Mehdi Yousefiabc*
Publishing models and article dates explained

referentielijst van dendritische celtherapie met T-car cells - TIL - tumor Infilytrating Lymfocyten

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