NL79 RABO 0372931138 t.n.v. Stichting Gezondheid Actueel in Terneuzen. BIC/SWIFTCODE RABONL2U.
30 december 2025: Bron: The Journal of Liquid Biopsy d.d. juni 2025
Een vloeibare biopsie / bloedtest is bij borstkanker uitgegroeid tot misschien wel een van de belangrijkste diagnose methodes voor alle vormen van borstkanker. En wordt zowel preventief gebruikt als diagnosemiddel voor een te geven behandeling bij het vaststellen van tumorDNA. Ook kan een vloeibare biopsie / bloedtest gebruikt worden bij het controleren van de tumormarkers en daarmee het controleren van de effectiviteit van een behandeling.
Omdat een vloeibare biopsie / bloedtest een minimaal invasieve methode blijkt voor het analyseren van circulerende tumorcellen (CTC's), celvrij DNA (cfDNA), circulerend tumor-DNA (ctDNA), extracellulaire blaasjes (EV's) en andere van tumoren afgeleide biomarkers in lichaamsvloeistoffen wordt deze methode gezien als het belangrijkste hulpmiddel bij ook andere vormen van kanker.
In het Journal of Liquid biopsy is afgelopen zomer een studieverslag gepresenteerd dat de impact en huidige staat van gebruik en onderzoek van een vloeibare biopsie / bloedtest bij borstkanker beschrijft aan de hand van de literatuur.
Uit het studieverslag gekopieerd een grafische afbeelding van de mogelijkheden van een vloeibare biopsie / bloedtest:

Fig. 1
Naast andere hoofdstukken in het studieverslag staat onder de kop: "Impact of liquid biopsy on patient outcomes" hoe een vloeibare biopsie / bloedtest informatie kan geven tijdens een behandeling bij borstkanker:
- De integratie van een vloeibare biopsie / bloedtest in de klinische praktijk heeft de potentie om de uitkomsten voor patiënten op verschillende manieren aanzienlijk te beïnvloeden [220].
- Een vloeibare biopsie / bloedtest heeft veelbelovende resultaten laten zien bij het opsporen van borstkanker in een vroeger stadium in vergelijking met traditionele beeldvormingsmethoden. Vroege detectie maakt tijdige interventie mogelijk en kan de overlevingskansen verbeteren door de ziekte aan te pakken voordat deze zich verder ontwikkelt [28,220].
- Een vloeibare biopsie / bloedtest maakt de identificatie mogelijk van specifieke genetische mutaties en veranderingen die kunnen leiden tot gepersonaliseerde behandelstrategieën. Door therapieën af te stemmen op het moleculaire profiel van de tumor, kunnen artsen de effectiviteit van de behandeling verbeteren en bijwerkingen verminderen [25].
- Een vloeibare biopsie / bloedtest biedt realtime monitoring van de tumordynamiek, waardoor behandelplannen kunnen worden aangepast op basis van de respons van de patiënt [221]. Deze mogelijkheid helpt bij het vroegtijdig identificeren van resistentie en het aanpassen van therapieën om de resultaten te verbeteren. Het niet-invasieve karakter van een vloeibare biopsie / bloedtest vermindert de noodzaak voor frequente weefselbiopsieën, die oncomfortabel en risicovol kunnen zijn[25,221]. Dit aspect is met name gunstig voor patiënten die regelmatige monitoring nodig hebben of patiënten met uitgezaaide ziekte.
Het volledige studierapport is gratis in te zien. Klik op de titel van het abstract.
The impact of liquid biopsy in breast cancer: Redefining the landscape of non-invasive precision oncology
Under a Creative Commons license
Open access
Outline
- Abstract
- Keywords
- 1. Introduction
- 2. Spectrum of liquid biopsy
- 3. Applications of liquid biopsy in BC
- 4. Technological advances and challenges
- 5. Clinical trials and evidence
- 6. Future directions and emerging trends
- 7. Conclusion
- Data availability statement
- Funding
- Declaration of competing interest
- Acknowledgements
- References
Tables (4)
Zie de honderden referenties onder:Data availability statement
Data sharing does not apply to this article as no new data were created or analyzed in this study.
Funding
NIL.
Declaration of competing interest
The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: No conflict of Intrests If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Acknowledgements
NIL.
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Reageer op "Vloeibare biopsie (bloedtest) op zoek naar circulerend tumor-DNA (ctDNA) is een steeds vaker gebruikte methode bij de preventie, diagnose en behandelingen van borstkanker. Hier een uitleg aan de hand van de literatuur."