Zie ook in gerelateerde artikelen hiernaast of hieronder

5 februari 2026: Bron: Advanced Healthcare Materials d.d. 29 januari 2026 en Massachusetts Institute of Technology

Een draagbaar apparaatje dat via ultrasound scans kan maken maakt vroege opsporing mogelijk van kwaadaardige tumoren van het type borstkanker. Maar zou ook gebruikt kunnen worden voor andere vormen van kanker. Dit draagbare echo-apparaat zou overal gebruikt kunnen worden zowel thuis als in de dokterspraktijk.

Het nieuwe systeem bestaat uit een kleine echografiesonde die is verbonden met een acquisitie- en verwerkingsmodule die iets groter is dan een smartphone. Dit systeem kan onderweg worden gebruikt door het aan te sluiten op een laptop om in realtime breedbeeld 3D-beelden te reconstrueren en te bekijken.
"Alles is compacter, waardoor het gemakkelijker te gebruiken is in landelijke gebieden of voor mensen die mogelijk belemmeringen ondervinden bij het gebruik van dit soort technologie", zegt Canan Dagdeviren, universitair hoofddocent mediawetenschappen aan het Massachusetts Institute of Technology (MIT) en hoofdauteur van de studie.
Met dit systeem, zegt ze, zouden mogelijk meer tumoren in een vroeg stadium kunnen worden opgespoord, wat de kans op een succesvolle behandeling vergroot.

Bovenstaande tekst is gedeeltelijk vertaald uit de informatie die op de website van het Massachusetts Institute of Technology staat.

Het volledige studieverslag is gratis in te zien of te downloaden. Klik daarvoor op de titel van het abstract dat in tegenstelling tot het volledige studierapport een summiere omschrijving geeft:

Real-Time 3D Ultrasound Imaging with an Ultra-Sparse, Low Power Architecture

Colin Marcus, Md Osman Goni Nayeem, Aastha Shah, Jason Hou, Shrihari Viswanath, Maya Eusebio, David Sadat, Anantha P. Chandrakasan, Tolga Ozmen, Canan Dagdeviren

First published: 29 January 2026

https://doi.org/10.1002/adhm.202505310Digital Object Identifier (DOI)

Colin Marcus and Md Osman Goni Nayeem contributed equally to this work.

ABSTRACT

Effective resource-constrained volumetric ultrasound imaging requires compact, low-power systems capable of wide-angle real-time 3D imaging to accommodate small changes in placement by the operator. However, obtaining such images requires an excessive O(N2) channel count, bulky electronics, and high power consumption. We introduce an end-to-end system architecture to enable high-resolution, real-time 3D ultrasound imaging in a portable form factor. We present: a convolutional optimally distributed array (CODA) geometry that drastically reduces the number of elements (from 1024 to 128), a novel chirped data acquisition (cDAQ) architecture that enhances imaging depth while operating with a 25.3 dB lower transmit amplitude than a pulsed system, and an associated new signal processing methodology. We experimentally demonstrate our system's ability to perform deep (> 11 cm), high axial resolution (< 600 µm), and wide-angle (57°) imaging, while simultaneously reducing power consumption (29.6x reduction) and drive voltage (18 V). We validated our system in vitro and further performed in vivo human trials, demonstrating the ability to detect both tumors and cysts in breast tissue. This new architectural approach will unlock a new class of medical devices with enhanced diagnostic and long-term monitoring capabilities and open up future wearable designs of real-time 3D ultrasound systems.

Referenties:

1X. Jiang and A. M. Al-Jumaily, “Ultrasound Transducers for Biomedical Imaging and Therapy,” Journal of Engineering and Science in Medical 1 (2018): 040201.
Google Scholar
2W. A. Kalender, “X-Ray Computed Tomography,” Physics in Medicine and Biology 51 (2006): R29–R43, https://doi.org/10.1088/0031-9155/51/13/R03.

PubMed Web of Science®Google Scholar
3S. M. Bierig and A. Jones, “Accuracy and Cost Comparison of Ultrasound Versus Alternative Imaging Modalities, Including CT, MR, PET, and Angiography,” Journal of Diagnostic Medical Sonography 25 (2009): 138–144, https://doi.org/10.1177/8756479309336240.

Web of Science®Google Scholar
4L. Zhang, W. Du, J. Kim, C. Yu, and C. Dagdeviren, “An Emerging Era: Conformable Ultrasound Electronics,” Advanced Materials 36 (2024): 2307664.

CAS Web of Science®Google Scholar
5J. Kim, H. Yoon, S. Viswanath, and C. Dagdeviren, “Conformable Piezoelectric Devices and Systems for Advanced Wearable and Implantable Biomedical Applications,” Annual Review of Biomedical Engineering 27 (2025): 255–282, https://doi.org/10.1146/annurev-bioeng-020524-121438.

CAS PubMed Web of Science®Google Scholar
6C. C. Yu, A. Shah, N. Amiri, et al., “A Conformable Ultrasound Patch for Cavitation-Enhanced Transdermal Cosmeceutical Delivery,” Advanced Materials 35 (2023): 2300066.

CAS Web of Science®Google Scholar
7J. F. Hou, M. O. G. Nayeem, K. A. Caplan, et al., “An Implantable Piezoelectric Ultrasound Stimulator (ImPULS) for Deep Brain Activation,” Nature Communications 15 (2024): 4601, https://doi.org/10.1038/s41467-024-48748-6.

CAS PubMed Web of Science®Google Scholar
8S. Zhou, X. Gao, G. Park, et al., “Transcranial Volumetric Imaging Using a Conformal Ultrasound Patch,” Nature 629 (2024): 810–818, https://doi.org/10.1038/s41586-024-07381-5.

CAS PubMed Web of Science®Google Scholar
9H. Hu, H. Huang, M. Li, et al., “A Wearable Cardiac Ultrasound Imager,” Nature 613 (2023): 667–675, https://doi.org/10.1038/s41586-022-05498-z.

CAS PubMed Web of Science®Google Scholar
10M. Lin, Z. Zhang, X. Gao, et al., “A Fully Integrated Wearable Ultrasound System to Monitor Deep Tissues in Moving Subjects,” Nature Biotechnology 42 (2023): 448–457, https://doi.org/10.1038/s41587-023-01800-0.

PubMed Web of Science®Google Scholar
11S. Vostrikov, J. Tille, L. Benini, and A. Cossettini, “TINYPROBE: A Wearable 32-Channel Multimodal Wireless Ultrasound Probe,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control 72, no. 1 (2025): 64–76, https://doi.org/10.1109/TUFFC.2024.3496474.

PubMed Web of Science®Google Scholar
12C. Wang, X. Chen, L. Wang, et al., “Bioadhesive Ultrasound for Long-Term Continuous Imaging of Diverse Organs,” Science 377 (2022): 517–523, https://doi.org/10.1126/science.abo2542.

CAS PubMed Web of Science®Google Scholar
13L. Zhang, C. Marcus, D. Lin, et al., “A Conformable Phased-Array Ultrasound Patch for Bladder Volume Monitoring,” Nature Electronics 7 (2024): 77–90, https://doi.org/10.1038/s41928-023-01068-x.

Web of Science®Google Scholar
14W. Du, L. Zhang, E. Suh, et al., “Conformable Ultrasound Breast Patch for Deep Tissue Scanning and Imaging,” Science Advances 9 (2023): adh5325, https://doi.org/10.1126/sciadv.adh5325.

Web of Science®Google Scholar
15J. A. Jensen, M. Schou, L. T. Jorgensen, et al., “Anatomic and Functional Imaging Using Row–Column Arrays,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control 69 (2022): 2722–2738, https://doi.org/10.1109/TUFFC.2022.3191391.

PubMed Web of Science®Google Scholar
16H. Bouzari, M. Engholm, C. Beers, et al., “Curvilinear 3-D Imaging Using Row–Column-Addressed 2-D Arrays With a Diverging Lens: Phantom Study,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control 65 (2018): 1182–1192, https://doi.org/10.1109/TUFFC.2018.2836384.

PubMed Web of Science®Google Scholar
17E. Roux, F. Varray, L. Petrusca, C. Cachard, P. Tortoli, and H. Liebgott, “Experimental 3-D Ultrasound Imaging With 2-D Sparse Arrays using Focused and Diverging Waves,” Scientific Reports 8 (2018): 9108.

PubMed Web of Science®Google Scholar
18R. Cohen, N. Fingerhut, F. Varray, H. Liebgott, and Y. C. Eldar, “Sparse Convolutional Beamforming for 3-D Ultrafast Ultrasound Imaging,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control 68 (2021): 2444–2459, https://doi.org/10.1109/TUFFC.2021.3068078.

PubMed Web of Science®Google Scholar
19R. Y. Chiao and X. Hao, “Coded Excitation for Diagnostic Ultrasound: A System Developer's Perspective,” IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control 52 (2005): 160–170, https://doi.org/10.1109/TUFFC.2005.1406543.

PubMed Web of Science®Google Scholar
20J. Song, S. Kim, H. Sohn, T. Song, and Y. M. Yoo, “Coded Excitation for Ultrasound Tissue Harmonic Imaging,” Ultrasonics 50 (2010): 613–619, https://doi.org/10.1016/j.ultras.2010.01.001.

PubMed Web of Science®Google Scholar
21M. O'Donnell and Y. Wang, “Coded Excitation Methods in Biomedical Ultrasound,” in 2004 2nd IEEE Int. Symposium on Biomedical Imaging: Macro to Nano (IEEE Cat No. 04EX821) (IEEE, 2004): 37–40, https://doi.org/10.1109/ISBI.2004.1398468.

Google Scholar
22V. L. Newhouse, D. Cathignol, and J. Y. Chapelon, “ Introduction to Ultrasonic Pseudo-Random Code Systems,” Progress in Medical Imaging (Springer, 1988): 215–226, https://doi.org/10.1007/978-1-4612-3866-9_5.

Google Scholar
23T. X. Misaridis, K. Gammelmark, C. H. Jørgensen, et al., “Potential of Coded Excitation in Medical Ultrasound Imaging,” Ultrasonics 38 (2000): 183–189, https://doi.org/10.1016/S0041-624X(99)00130-4.

CAS PubMed Web of Science®Google Scholar
24J. Mamou, J. A. Ketterling, and R. H. Silverman, “Chirp-Coded Excitation Imaging With a High-Frequency Ultrasound Annular Array,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control 55 (2008): 508–513, https://doi.org/10.1109/TUFFC.2008.670.

PubMed Web of Science®Google Scholar
25X. Wang, J. Yang, J. Ji, Y. Zhang, and S. Zhou, “Research on Golay-Coded Excitation in Real-Time Imaging of High Frequency Ultrasound Biomicroscopy,” Scientific Reports 11 (2021): 1848.

CAS PubMed Web of Science®Google Scholar
26A. Lahav, T. Chernyakova, and Y. C. Eldar, “FoCUS: Fourier-Based Coded Ultrasound,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control 64 (2017): 1828–1839, https://doi.org/10.1109/TUFFC.2017.2760359.

PubMed Web of Science®Google Scholar
27T. Misaridis and J. A. Jensen, “Use of Modulated Excitation Signals in Medical Ultrasound. Part I: Basic Concepts and Expected Benefits,” IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control 52 (2005): 177–191, https://doi.org/10.1109/TUFFC.2005.1406545.

PubMed Web of Science®Google Scholar
28T. Misaridis and J. A. Jensen, “Use of Modulated Excitation Signals in Medical Ultrasound. Part II: Design and Performance for Medical Imaging Applications,” IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control 52 (2005): 192–207, https://doi.org/10.1109/TUFFC.2005.1406546.

PubMed Web of Science®Google Scholar
29T. Misaridis and J. A. Jensen, “Use of Modulated Excitation Signals in Medical Ultrasound. Part III: High Frame Rate Imaging,” IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control 52 (2005): 208–219, https://doi.org/10.1109/TUFFC.2005.1406547.

PubMed Web of Science®Google Scholar
30C. C. Shen and P. Y. Hsieh, “Ultrasound Baseband Delay-Multiply-and-Sum (BB-DMAS) Nonlinear Beamforming,” Ultrasonics 96 (2019): 165–174, https://doi.org/10.1016/j.ultras.2019.01.010.

PubMed Web of Science®Google Scholar
31 Evaluation of Thermal Effects of Medical Devices That Produce Tissue Heating And/Or Cooling; Draft Guidance for Industry and Food and Drug Administration Staff.
Google Scholar
32J. Rouyer, S. Mensah, É. Franceschini, P. Lasaygues, and J. P. Lefebvre, “Conformal Ultrasound Imaging System for Anatomical Breast Inspection,” IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control 59 (2012): 1457–1469, https://doi.org/10.1109/TUFFC.2012.2346.

PubMed Web of Science®Google Scholar
33R. Guo, G. Lu, B. Qin, and B. Fei, “Ultrasound Imaging Technologies for Breast Cancer Detection and Management: A Review,” Ultrasound in Medicine & Biology 44 (2018): 37–70, https://doi.org/10.1016/j.ultrasmedbio.2017.09.012.

PubMed Web of Science®Google Scholar
34Q. Zhou, K. H. Lam, H. Zheng, W. Qiu, and K. K. Shung, “Piezoelectric Single Crystal Ultrasonic Transducers for Biomedical Applications,” Progress in Materials Science 66 (2014): 87–111, https://doi.org/10.1016/j.pmatsci.2014.06.001.

CAS PubMed Web of Science®Google Scholar
35S. V. Fernandez, J. H. Kim, D. Sadat, et al., “A Dynamic Ultrasound Phantom with Tissue-Mimicking Mechanical and Acoustic Properties,” Advanced Science 11 (2024): 2400271.

CAS PubMed Web of Science®Google Scholar