31 mei 2011: zie ook de nieuwste bevindingen van het WCRF over de relatie tussen leefstijl en voeding en het risico op (darm) kanker. Klik hier voor nieuwste studiegegevens
Actuele ontwikkelingen over therapeutische behandelingen van darmkankers zijn te lezen onder kankersoorten-darmkankers
Acht of meer glazen bier (21.7%; OR = 2.43; 95% CI = 1.11-5.32; p= 0.02) of acht of meer glazen sterk alcoholische drankjes (26.3%; OR = 2.53; 95% CI = 1.10-4.28; p < 0.01) per week geven ca. 20% groter risico op ontwikkelen van darmkankers. Een tot acht glazen rode wijn per week vermindert daarentegen het risico op darmkanker (OR = 0.55; 95% CI = 0.34-0.87; p < 0.01). Dit alles blijkt uit een studie onder 2.291 patiënten vooraf aan een colonscopie en deze week gepubliceerd in de toonaangevende American Journal of Gastroenterology
21 september 2005: Bron: Am J Gastroenterol. 2005 Sep;100(9):2049-55.
Am J Gastroenterol. 2005 Sep;100(9):2049-55.<
Prevalence and risk of colorectal neoplasia in consumers of alcohol in a screening population.
Anderson JC, Alpern Z, Sethi G, Messina CR, Martin C, Hubbard PM, Grimson R, Ells PF, Shaw RD. Department of Gastroenterology and Hepatology, Stony Brook University, Stony Brook, New York.
BACKGROUND AND AIMS: Although studies suggest a positive association between alcohol consumption and risk for colorectal neoplasia, the impact on screening has not been fully examined. It is also unclear whether all types of alcohol are associated with an increased risk. We performed a cross-sectional study to examine the impact of regular alcohol consumption on the detection of significant colorectal neoplasia in a screening population.
METHODS: Data collected for 2,291 patients presenting for screening colonoscopy: known risk factors for colorectal neoplasia and alcohol drinking pattern. Our outcome was the endoscopic detection of significant colorectal neoplasia, which included adenocarcinoma, high-grade dysplasia, villous tissue, adenomas 1 cm or greater and multiple (>2) adenomas of any size.
RESULTS: When compared to abstainers, we found an increased risk for significant neoplasia in those patients who consumed more than eight drinks of spirits alcohol (26.3%; OR = 2.53; 95% CI = 1.10-4.28; p < 0.01) and those who drank more than eight servings of beer per week (21.7%; OR = 2.43; 95% CI = 1.11-5.32; p= 0.02). Consuming one to eight glasses of wine per week was associated with a decreased risk for significant neoplasia (OR = 0.55; 95% CI = 0.34-0.87; p < 0.01).
CONCLUSIONS: While there was a more than twofold increased risk of significant colorectal neoplasia in people who drink spirits and beer, people who drank wine had a lower risk. In our sample, people who drank more than eight servings of beer or spirits per week had at least a one in five chance of having significant colorectal neoplasia detected by screening colonoscopy. (Am J Gastroenterol 2005;100:1-7). PMID: 16128951 [PubMed - in process]