Actuele ontwikkelingen over therapeutische behandelingen van eierstokkanker zijn te lezen onder kankersoorten-eierstokkanker

14 december 2005: Bron: Medscape en Arch Intern Med. 2005;165:2683-2686

Een grote prospectieve epidemologische Zweedse bevolkingstudie toont aan dat vrouwen die elke dag twee tot drie koppen thee drinken hun risico op eierstokkanker verminderen met 50%. Dit klinkt als erg veel maar in prospectieve studies worden al snel dit soort percentages gevonden en liggen de uitersten in de statistische reeks van cijfers vaak ver uit elkaar. Toch zegt deze studie wel iets en wereldwijd wordt aan deze studie dan ook best veel aandacht gegeven. O.a. in Medscape, zie hieronder het artikel dat zij eraan wijden. Onder Medscape kunt u de details van deze onderstaande studie ook teruglezen.

Bron: Medscape en Arch Intern Med. 2005;165:2683-2686

Dec. 13, 2005 — Tea consumption is associated with a reduced risk for ovarian cancer, according to the results of a large, prospective, population-based study reported in the December 12/26 issue of the Archives of Internal Medicine.

"Substantial evidence from laboratory studies indicates that green and black tea preparations may protect against various cancers," write Susanna C. Larsson, MSc, and Alicja Wolk, DMSc, from Karolinska Institutet in Stockholm, Sweden. "Few epidemiologic studies, however, have examined the relationship specifically between tea consumption and risk of ovarian cancer."

The investigators evaluated the association between tea consumption and risk for ovarian cancer in 61,057 women aged 40 to 76 years who were enrolled in the Swedish Mammography Cohort between 1987 and 1990. These women completed a validated 67-item food frequency questionnaire (FFQ) at enrollment and were followed up for cancer incidence through December 2004.

During an average follow-up of 15.1 years, there were 301 incident cases of invasive epithelial ovarian cancer. After controlling for potential confounders, tea consumption was inversely associated with ovarian cancer risk (P for trend, .03). Compared with women who never drank tea or drank it less than monthly, those who consumed less than 1 cup per day, 1 cup per day, and 2 or more cups per day had multivariate hazard ratios (HRs) of 0.82 (95% confidence interval , 0.62 - 1.08), 0.76 (95% CI, 0.56 - 1.04), and 0.54 (95% CI, 0.31 - 0.91), respectively. Each additional cup of tea consumed per day was associated with an 18% reduction in risk for ovarian cancer (multivariate HR, 0.82; 95% CI, 0.68 - 0.99).

"These results suggest that tea consumption is associated with a reduced risk of epithelial ovarian cancer in a dose-response manner," the authors write. "This association does not depend on lower coffee consumption among women with high tea consumption; coffee is not associated with ovarian cancer risk in this cohort."

Study limitations include observational design, possible uncontrolled or residual confounding by a healthy lifestyle, and random effects of chance. "Our results from a large population-based cohort of Swedish women suggest that tea consumption may lower the risk of ovarian cancer," the authors conclude. "Because prospective data on this relationship are scarce, our findings need confirmation by future studies."

The Swedish Cancer Foundation and the Swedish Research Council/Longitudinal Studies supported this research.

Arch Intern Med. 2005;165:2683-2686


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