6 maart 2023:

Aanvullend op onderstaand artikel hier een update van hoe je leverproblemen door alcoholgebruik kan voorkomen mocht het je niet lukken helemaal te stoppen met alcoholgebruik.

mannen en vrouwen wordt geadviseerd om regelmatig niet meer dan 14 eenheden per week te drinken
Een eenheid alcohol is gelijk aan ongeveer een halve liter pils van normale sterkte of een maatbeker (25 ml) sterke drank.
verspreid uw drinken over 3 dagen of meer als u maar liefst 14 eenheden per week drinkt als je wilt minderen, probeer dan elke week een aantal drankvrije dagen te houden
Zelfs als u jarenlang een zware drinker bent geweest, zal het verminderen of stoppen van uw alcoholinname belangrijke korte- en langetermijnvoordelen hebben voor uw lever en algehele gezondheid.

Zie verder dit artikel: https://www.nhs.uk/conditions/alcohol-related-liver-disease-arld/

23 april 2011: bron Medscape

Frequent gebruik van alcohol is vaak de oorzaak van problemen met de lever tot aan primaire leverkanker aan toe. Op Medscape is een 14 pagina's groot studieverslag geplaatst over hoe op dit moment leverproblemen worden behandeld. Waarbij een grote nadruk ligt op leefstijl, proberen af te komen van alcohol gebruik, en gezonde voeding en voedingsmiddelen als behandelingsvorm. Maar ook is er aandacht voor agressievere manieren om een zieke lever te behandelen. Hier een inleiding tot het artikel met een deeplink naar het totale artikel en onderaan de referentielijst die gebruikt is voor het artikel.

Hoe behandel je een zieke lever veroorzaakt door alcohol?

Bron: Medscape

Treatment of Alcoholic Liver Disease

Thomas H. Frazier, MD; Abigail M. Stocker, MD; Nicole A. Kershner, MD; Luis S. Marsano, MD; Craig J. McClain, MD

Authors and Disclosures

Abstract and Introduction

Abstract

Alcoholic liver disease (ALD) remains a major cause of liver-related mortality in the US and worldwide. The correct diagnosis of ALD can usually be made on a clinical basis in conjunction with blood tests, and a liver biopsy is not usually required. Abstinence is the hallmark of therapy for ALD, and nutritional therapy is the first line of therapeutic intervention. The role of steroids in patients with moderate to severe alcoholic hepatitis is gaining increasing acceptance, with the caveat that patients be evaluated for the effectiveness of therapy at 1 week. Pentoxifylline appears to be especially effective in ALD patients with renal dysfunction/hepatorenal syndrome. Biologics such as specific anti-TNFs have been disappointing and should probably not be used outside of the clinical trial setting. Transplantation is effective in patients with end-stage ALD who have stopped drinking (usually for ≥6 months), and both long-term graft and patient survival are excellent.

Introduction

Alcoholic liver disease (ALD), which ranges from simple steatosis to cirrhosis and hepatocellular carcinoma (HCC), continues to represent a major health issue in the United States and abroad. Despite significant advances in the understanding of the pathogenesis of alcohol-related liver injury, there are no FDA-approved treatments for ALD. The purpose of this review is to examine the diagnosis and current modalities of treatment for ALD. At present, abstinence remains the cornerstone for successful treatment of ALD. Aside from treatment of the underlying addiction, aggressive nutritional intervention and 'off-label' use of various pharmacotherapies aimed at the underlying mechanisms of injury (e.g., cytokine dysregulation, endotoxin translocation and oxidative stress) represent our approach to treating ALD. Read more>>>>>>>>>>

Funding

This work was supported by NIH (grant numbers P01AA017103, P30AA019360, R01AA015970, R01AA018016, R01AA018869, R37AA010762, RC2AA019385, R01DK071765), the Veterans Administration (grant number BX000350), and the University of Louisville’s Center for Environmental Genomics and Integrative Biology (CEGIB) (grant number P30ES014443).

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Conflict of interest statement

None declared.

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