3 oktober 2010: Bron: Cancer Epidemiol Biomarkers Prev. 2010 Sep;19(9):2278-86. Epub 2010 Aug 31.

Longkanker is gedeeltelijk te voorkomen wanneer men regelmatig en gevarieerd groenten en fruit eet. Dit is de uitkomst van een grote Europese studie naar het effect van eetgewoontes. Mensen die gevarieerd eten en vooral groenten en fruit hebben 23% minder risico op het krijgen van longkanker. Al geldt dit in mindere mate voor rokers. Wie niet rookt heeft nog een veel grotere kans op geen longkanker te kriijgen. Het gaat wel om het type plaveiselcarcinooom van longkanker en bv. niet over longkanker veroorzaakt door asbest bv.

Klik hier voor een artikel van Medscape n.a.v. de gepubliceerde studie, waarvan hieronder het abstract behorend bij de studie: 

References

  1. World Cancer Research Fund/American Institute for Cancer Research. Food, nutrition, physical activity, and prevention of cancer: a global perspective. Washington, DC: American Institute for Cancer Research; 2007. Available at: http://www.dietandcancerreport.org/ Accessed September 14, 2010.

Cancer Epidemiol Biomarkers Prev. 2010 Sep;19(9):2278-86. Epub 2010 Aug 31.

Variety in fruit and vegetable consumption and the risk of lung cancer in the European prospective investigation into cancer and nutrition.

Büchner FL, Bueno-de-Mesquita HB, Ros MM, Overvad K, Dahm CC, Hansen L, Tjønneland A, Clavel-Chapelon F, Boutron-Ruault MC, Touillaud M, Kaaks R, Rohrmann S, Boeing H, Nöthlings U, Trichopoulou A, Zylis D, Dilis V, Palli D, Sieri S, Vineis P, Tumino R, Panico S, Peeters PH, van Gils CH, Lund E, Gram IT, Braaten T, Sánchez MJ, Agudo A, Larrañaga N, Ardanaz E, Navarro C, Argüelles MV, Manjer J, Wirfält E, Hallmans G, Rasmuson T, Key TJ, Khaw KT, Wareham N, Slimani N, Vergnaud AC, Xun WW, Kiemeney LA, Riboli E.

National Institute ofPublicHealth and the Environment, Bilthoven, The Netherlands. frederike.buchner@rivm.nl

Abstract

BACKGROUND: We investigated whether a varied consumption of vegetables and fruits is associated with lower lung cancer risk in the European Prospective Investigation into Cancer and Nutrition study.

METHODS: After a mean follow-up of 8.7 years, 1,613 of 452,187 participants with complete information were diagnosed with lung cancer. Diet diversity scores (DDS) were used to quantify the variety in fruit and vegetable consumption. Multivariable proportional hazards models were used to assess the associations between DDS and lung cancer risk. All models were adjusted for smoking behavior and the total consumption of fruit and vegetables.

RESULTS: With increasing variety in vegetable subgroups, risk of lung cancer decreases [hazard ratios (HR), 0.77; 95% confidence interval (CI), 0.64-0.94 highest versus lowest quartile; P trend = 0.02]. This inverse association is restricted to current smokers (HR, 0.73; 95% CI, 0.57-0.93 highest versus lowest quartile; P trend = 0.03). In continuous analyses, in current smokers, lower risks were observed for squamous cell carcinomas with more variety in fruit and vegetable products combined (HR/two products, 0.88; 95% CI, 0.82-0.95), vegetable subgroups (HR/subgroup, 0.88; 95% CI, 0.79-0.97), vegetable products (HR/two products, 0.87; 95% CI, 0.79-0.96), and fruit products (HR/two products, 0.84; 95% CI, 0.72-0.97).

CONCLUSION: Variety in vegetable consumption was inversely associated with lung cancer risk among current smokers. Risk of squamous cell carcinomas was reduced with increasing variety in fruit and/or vegetable consumption, which was mainly driven by the effect in current smokers.

IMPACT: Independent from quantity of consumption, variety in fruit and vegetable consumption may decrease lung cancer risk.

PMID: 20807832 [PubMed - in process]

 


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