17 januari 2017: Lees ook deze review studie van de Cochrane: Library Exercise for women receiving adjuvant therapy for breast cancer. 


Exercise during adjuvant treatment for breast cancer can be regarded as a supportive self care intervention that probably results in less fatigue, improved physical fitness, and little or no difference in cancer-specific quality of life and depression. Exercise may also slightly improve cancer site-specific quality of life and cognitive function, while it may result in little or no difference in health-related quality of life.

5 juni 2005: Bron: Support Care Cancer. 2005 Apr 23; en Support Care Cancer. 2002 Apr;10(3):237-46.<

Spierontspanningsoefeningen en geleide visualisatie verminderen samen de angst voor chemo, depressiviteit en opstandigheid bij patienten die chemo voor hun borstkanker kregen. Na een half jaar was in de interventiegroep de kwaliteit van leven aantoonbaar beter dan in de controlegroep van beide 30 patiënten. Opvallend was ook dat in de groep van paitënten die spierontspanningsoefeningen en visualisatie deden braken en misselijkheid aantoonbaar veel minder voorkwam dan bij de patiënten in de controlegroep. Onder abstract van eerst genomede studie staat een vergelijkbare studie van een jaar eerder met zelfde resultaten.

Efficacy of progressive muscle relaxation training and guided imagery in reducing chemotherapy side effects in patients with breast cancer and in improving their quality of life.

Yoo HJ, Ahn SH, Kim SB, Kim WK, Han OS.

Department of Psychiatry, Asan Medical Center, University of Ulsan College of Medicine, # 388-1, Pungnap-dong Songpa-gu, 138-736, Seoul, South Korea, junhkl@hanafos.com.

GOALS: This study was designed to assess the effectiveness of progressive muscle relaxation training (PMRT) and guided imagery (GI) in reducing the anticipatory nausea and vomiting (ANV) and postchemotherapy nausea and vomiting (PNV) of patients with breast cancer and to measure their effects on the patients' quality of life (QoL).

PATIENTS AND METHODS: Thirty chemotherapy-naive patients with breast cancer were randomized to the PMRT and GI group and 30 to the control group. Before each of six cycles of adjuvant chemotherapy, each patient was administered a self-report Multiple Affect Adjective Checklist (MAACL), and incidents of ANV and PNV for the first three postchemotherapy days were recorded. All patients were administered the Functional Assessment of Cancer Therapy-Breast (FACT-B) at baseline and after 3 and 6 months.

RESULTS: We found that the PMRT and GI group was significantly less anxious, depressive, and hostile than the control group. We also found that the PMRT and GI group experienced significantly less ANV and PNV and that 6 months after CT, the QoL of the PMRT and GI group was higher than that of the control group. CONCLUSION: These results indicate that PMRT and GI were associated with both the improvements in ANV and PNV and in the QoL of patients with breast cancer.

PMID: 15856335 [PubMed - as supplied by publisher]

Support Care Cancer. 2002 Apr;10(3):237-46.

The effectiveness of progressive muscle relaxation training in managing chemotherapy-induced nausea and vomiting in Chinese breast cancer patients: a randomised controlled trial.

Molassiotis A, Yung HP, Yam BM, Chan FY, Mok TS.
University of Nottingham, School of Nursing, A Floor, Medical School, Queen's Medical Centre, Nottingham, NG7 2UH, UK. Alexander.Molassiotis@nottingham.ac.uk

This study was a randomised controlled trial designed to assess the effectiveness of progressive muscle relaxation training (PMRT) in the clinical management of chemotherapy-related nausea and vomiting as an adjuvant intervention to accompany pharmacological antiemetic treatment (metoclopramide and dexamethasone i.v.). Seventy-one chemotherapy-naive breast cancer patients of an outpatient oncology unit of a university hospital in Hong Kong participated, with 38 subjects randomised to the experimental group and 33 to the control group. The intervention included the use of PMRT 1 h before chemotherapy was administered and daily thereafter for another 5 days (for a total of six PMRT sessions). Each session lasted for 25 min and was followed by 5 min of imagery techniques. The instruments used for data collection included the Chinese versions of the Profile of Mood States and the State-Trait Anxiety Inventory (measured before chemotherapy and then at day 7 and day 14 after chemotherapy), and the Morrow Assessment of Nausea and Vomiting Scale, which was used daily for the first 7 post-chemotherapy days. The use of PMRT considerably decreased the duration of nausea and vomiting in the experimental group compared with the control group ( P<0.05), whereas there were trends toward a lower frequency of nausea and vomiting ( P=0.07 and P=0.08 respectively). Neither nausea nor vomiting differed in intensity between the two groups. The significant effects were mainly evident on the first 4 post-chemotherapy days, when differences were statistically significant. Although there was a significantly less severe overall mood disturbance in the experimental group over time ( P<0.05), this did not apply in the case of anxiety. Such findings suggest that PMRT is a useful adjuvant technique to complement antiemetics for chemotherapy-induced nausea and vomiting and that incorporation of such interventions in the care plan can enhance the standards of care of cancer patients who experience side effects of chemotherapy. Publication Types:
Clinical Trial
Randomized Controlled Trial

PMID: 11904789 [PubMed - indexed for MEDLINE]

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