12 mei 2012: inmiddels wordt RFA - Radio frequency Ablation ook met de Ultra Sound techniek meer en meer toegepast. Zie voor meer recente informatie onder RFA - Radio Frequency Ablation informatie


31 mei 2006: Bron: 1: Br J Cancer. 2005 Oct 17;93(8):890-5.

Opereren van levertumoren en niertumoren met HIFU = High Dose Focused Ultrasound blijkt een veilig en met een beter resultaat, significante minder bijwerkingen, uit te voeren behandeling blijkt uit een gerandomiseerde fase II studie. Bij levertumoren werd een 100% verwijdering bereikt tegenover 67% bij niertumoren, maar ook in dit laatste geval nog beter dan bij andere traditionele operatieve technieken. Deze studie is gepubliceerd in het toonaangevende Britisch Journal of Cancer.

Als u hier klikt kunt u van onderstaande studie het volledige studie rapport gratis inzien. Onderaan dit artikel staat een referentielijst van studies gerelateerd aan HIFU - Ultra Sound en onderstaande studie


The safety and feasibility of extracorporeal high-intensity focused ultrasound (HIFU) for the treatment of liver and kidney tumours in a Western population

 Br J Cancer. 2005 October 17; 93(8): 890–895.
Published online 2005 September 27. doi:  10.1038/sj.bjc.6602803
PMCID: PMC2361666
The safety and feasibility of extracorporeal high-intensity focused ultrasound (HIFU) for the treatment of liver and kidney tumours in a Western population
R O Illing,1* J E Kennedy,1 F Wu,2 G R ter Haar,3 A S Protheroe,4 P J Friend,1 F V Gleeson,1 D W Cranston,1 R R Phillips,1 and M R Middleton4
1HIFU Unit, Churchill Hospital, Oxford OX3 7LJ, UK
2Clinical Center for Tumor Therapy, Chongqing University of Medical Sciences, People's Republic of China
3Institute of Cancer Research, Sutton, UK
4Cancer Research UK, Medical Oncology Unit, University of Oxford, Oxford, UK
*Author for correspondence: rowland@doctors.org.uk
Received May 3, 2005; Revised August 25, 2005; Accepted August 25, 2005.
High-intensity focused ultrasound (HIFU) provides a potential noninvasive alternative to conventional therapies. We report our preliminary experience from clinical trials designed to evaluate the safety and feasibility of a novel, extracorporeal HIFU device for the treatment of liver and kidney tumours in a Western population. The extracorporeal, ultrasound-guided Model-JC Tumor Therapy System (HAIFU™ Technology Company, China) has been used to treat 30 patients according to four trial protocols. Patients with hepatic or renal tumours underwent a single therapeutic HIFU session under general anaesthesia. Magnetic resonance imaging 12 days after treatment provided assessment of response. The patients were subdivided into those followed up with further imaging alone or those undergoing surgical resection of their tumours, which enabled both radiological and histological assessment. HIFU exposure resulted in discrete zones of ablation in 25 of 27 evaluable patients (93%). Ablation of liver tumours was achieved more consistently than for kidney tumours (100 vs 67%, assessed radiologically). The adverse event profile was favourable when compared to more invasive techniques. HIFU treatment of liver and kidney tumours in a Western population is both safe and feasible. These findings have significant implications for future noninvasive image-guided tumour ablation.
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