Zie ook: ALFYTAL module suppletie, deze sponsor uit onze reclamecaroussel levert al heel lang voedingsupplementen van hoge kwaliteit tegen heel acceptabele prijzen. Zoals pure broccolisprouts. 

5 augustus 2024: Bron:  2024 Jun; 16(11): 1583

Uit een grote meta-analyse van 12 observatiestudies en 23 case-control studies blijkt dat wie regelmatig broccoli eet het risico  op het krijgen van kanker verlaagt in vergelijking met wie weinig of geen broccoli eet. Er zijn in de afgelopen 25 jaar ook meerdere specifieke interventiestudies gedaan met broccoli, zie deze search op broccoli op onze website. Waaronder deze studie met rauwe broccoli bij blaaskanker en COPD. En deze meer algemene leefstijlstudie uit Denemarken.

Uit het abstract van de meta-analyse studie:

De resultaten suggereren een omgekeerd verband tussen de consumptie van broccoli en het risico op kanker, zowel in case-control studies (OR: 0,64, 95% CI van 0,58 tot 0,70, p < 0,001; Q = 35,97, p = 0,072, I2 = 30,49%- matige heterogeniteit; τ2 = 0,016) en observatiestudies (RR: 0,89, 95% BI van 0,82 tot 0,96, p = 0,003; Q = 13,51, p = 0,333, I2 = 11,21% – lage heterogeniteit; τ2 = 0,002). 

Het studierapport is gratis in te zien. Hier het abstract met referentielijst en geciteerde artikelen:

Abstract

Background: The scientific literature has reported an inverse association between broccoli consumption and the risk of suffering from several types of cancer; however, the results were not entirely consistent across studies. A systematic review and meta-analysis of observational studies were conducted to determine the association between broccoli consumption and cancer risk with the aim of clarifying the beneficial biological effects of broccoli consumption on cancer.

Methods: PubMed/MEDLINE, Web of Science, Scopus, Cochrane Library (CENTRAL), and Epistemonikos databases were searched to identify all published papers that evaluate the impact of broccoli consumption on the risk of cancer. Citation chasing of included studies was conducted as a complementary search strategy. The risk of bias in individual studies was assessed using the Newcastle-Ottawa Scale. A random-effects model meta-analysis was employed to quantitatively synthesize results, with the I2 index used to assess heterogeneity.

Results: Twenty-three case-control studies (n = 12,929 cases and 18,363 controls; n = 31,292 individuals) and 12 cohort studies (n = 699,482 individuals) were included in the meta-analysis. The results suggest an inverse association between broccoli consumption and the risk of cancer both in case-control studies (OR: 0.64, 95% CI from 0.58 to 0.70, p < 0.001; Q = 35.97, p = 0.072, I2 = 30.49%-moderate heterogeneity; τ2 = 0.016) and cohort studies (RR: 0.89, 95% CI from 0.82 to 0.96, p = 0.003; Q = 13.51, p = 0.333, I2 = 11.21%-low heterogeneity; τ2 = 0.002). Subgroup analysis suggested a potential benefit of broccoli consumption in site-specific cancers only in case-control studies.

Conclusions: In summary, the findings indicate that individuals suffering from some type of cancer consumed less broccoli, suggesting a protective biological effect of broccoli on cancer. More studies, especially cohort studies, are necessary to clarify the possible beneficial effect of broccoli on several types of cancer.

Keywords: anticancer agent; cancer prevention; chemopreventive; cruciferous vegetables; epidemiological studies; sulforaphane.

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Conflict of interest statement

The authors declare no conflicts of interest.

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