7 juli 2025: Bron: Nutrition & Metabolism volume 22, Article number: 27 (2025)

Rogge blijkt een uitstekend voedingsproduct om de bloedsuikerwaarden - insulinewaarde stabiel te houden, ook direct na het eten. Mede door het hoge vezelgehalte is rogge ook een prima voedingsproduct dat bv. ook de darmflora - darmmicrobiota gunstig beïnvloed.

Uit een meta-analyse van 31 studies blijkt dus dat rogge de bloedsuikerwaarden - insulinewaarde gunstig beïnvloedt. Met als belangrijkste conclusie: Overall, results of this meta-analysis suggest that rye consumption may reduce insulin postprandial AUC without affecting glucose markers. Is vertaalt in het Nederlands: Over het geheel genomen suggereren de resultaten van deze meta-analyse dat roggeconsumptie de postprandiale AUC van insuline kan verlagen zonder dat dit invloed heeft op glucosemarkers. 

Het volledige studieverslag is gratis in te zien, klik daarvoor op de titel van het abstract:

Effect of rye consumption on markers of glycemic control: evidence on the “rye factor”: a systematic review and meta-analysis of randomized controlled trials

Nutrition & Metabolism volume 22, Article number: 27 (2025) Cite this article

Abstract

  • Rye, as a source of dietary fiber, may have beneficial effects in glycemic control. In the current meta-analysis, we collected randomized controlled trials (RCTs) that examined the effect of rye consumption on glucose and insulin markers. PubMed, Scopus, and Web of Science databases were searched to find the RCTs. Random-effects model was used to calculate mean difference and 95% confidence intervals.
  • Thirty-one RCTs, including 922 participants, passed the screening and eligibility stages and were included in the meta-analysis. Rye consumption did not have a significant effect on glucose indices including fasting, postprandial, and area under the curve (AUC).
  • Subgroup analysis did not make a difference in the results, except that there was trends for increased postprandial glucose in two subgroups: individuals aged > 50 y (weighted mean difference (WMD) = 0.93, 95% CI: -0.03, 1.90 mmol/l, P = 0.058) and short intervention lengths (≤ 270 min) (WMD = 0.48, 95% CI: -0.03, 0.99 mmol/l, P = 0.066), and a trend for decreased AUC for glucose in rye fiber doses ≥ 12 g (WMD = -0.22, 95% CI: -0.46, 0.01 mmol/l, P = 0.059).
  • Rye consumption did not show an effect on fasting and postprandial insulin but indicated a reduction in AUC for insulin (WMD = -0.48, 95% CI: -0.66, -0.30 mU/l, P < 0.001).
  • Overall, results of this meta-analysis suggest that rye consumption may reduce insulin postprandial AUC without affecting glucose markers. Prospective cohorts are needed to determine the clinical importance of the finding.

Data availability

The datasets generated and/or analyzed during this meta-analysis are available from the corresponding author upon reasonable request.

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Authors and Affiliations

  1. Department of Community Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran

    Mohammad Ghazvini & Masoumeh Akhlaghi

  2. Endocrinology and Metabolism Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Science, Kerman, Iran

    Faezeh Ghanbari-Gohari

  3. Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran

    Sahar Foshati

Contributions

M. G. conceived the idea for the meta-analysis and conducted the primary search and screening. S. F. and M. A. completed the search and screening processes and performed data extraction. F. G. and M. A. wrote the manuscript and prepared the figures and tables. All the authors approved the final version of the manuscript.

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Correspondence to Masoumeh Akhlaghi.

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Ghazvini, M., Ghanbari-Gohari, F., Foshati, S. et al. Effect of rye consumption on markers of glycemic control: evidence on the “rye factor”: a systematic review and meta-analysis of randomized controlled trials. Nutr Metab (Lond) 22, 27 (2025). https://doi.org/10.1186/s12986-025-00901-8

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preventie, bloedsuikerwaarden, insulinewaarde, rogge, meta-analyse, diabetes-2, hart- en vaatziektes


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