12 maart 2019: Bron: PharmaNutrition Volume 7, March 2019, 100139

Ik schrijf dit artikel vanuit een internetcafe in Santo Domingo dus beperk me tot het studierapport en de kern van de studie.

Probiotica verbetert de kwaliteit van leven van patienten met Colitus Ulcerose (prikkelbare darm). Dit blijkt uit een kleinschalige Nederlandse studie. Gebruikers van probiotica rapporteerden vaak verbetering van kwaliteit van leven. Vooral de stoelgang en ontlasting verbeterde sterk.

Het volledige studierapport: 

Probiotics for improving quality of life in ulcerative colitis: Exploring the patient perspective 

is gratis in te zien.

Hier het abstract van de studie:


Volume 7, March 2019, 100139

Probiotics for improving quality of life in ulcerative colitis: Exploring the patient perspective

Under a Creative Commons license


Ulcerative colitis (UC) is known to burden patients in ways that are not always clinically apparent and therefore easily overlooked in conventional treatment regimens. The medical needs of UC patients thus may be unmet, calling for novel patient-centered approaches to alleviate disease impact and improve quality of life (QoL). Probiotics are suggested as a safe and effective addition to current regimens, but the clinical evidence base appears insufficient to support efficacy verdicts. This study therefore qualitatively explored UC’s impact on QoL from a patient perspective, and evaluated the potential of a multispecies probiotic for impact alleviation. Semi-structured interviews were held with 23 UC patients, who had either opted for a trial period with the multispecies probiotic Ecologic® 825 (n=14) or had not (n=9). The thematic analysis elucidates the broad nature of UC’s impact, identifying 5 core impact domains and effects throughout. Furthermore, as patients’ attitudes towards probiotics were predominantly positive, 57% of users reported positive impact of consumption, and the vast majority of these deemed this as (highly) relevant for improving QoL, the findings favor probiotic supplementation and warrant further clinical evaluation. In this regard, defecation frequency and stool texture seem promising outcome parameters for being most often reported.

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