Aan dit artikel is vele uren gewerkt. Opzoeken, vertalen, op de website plaatsen enz. Als u ons wilt ondersteunen dan kan dat via een al of niet anonieme donatie. Elk bedrag is welkom hoe klein ook. Klik hier als u ons wilt helpen kanker-actueel online te houden Wij zijn een ANBI organisatie en dus is uw donatie in principe aftrekbaar voor de belasting.

6 augustus 2015: dit bericht toch maar eens naar voren gehaald. Is echt interessant.

Lees dit volledige studierapport maar eens: Chemopreventive and Therapeutic Activity of Dietary Blueberry against Estrogen-Mediated Breast Cancer Gratis in te zien en met hele duidelijke grafieken waarin de blauwe bessen overal als beste uitkomen. Zowel preventief als therapeutisch. Zie ook referentielijst onderaan dit artikel

28 september 2011: bron: J Nutr. 2011 Oct;141(10):1805-12. Epub 2011 Aug 31

Een bosbessen extract in poedervorm toegediend bij muizen met agressieve vorm van borstkanker (triple negatief) blijkt de tumoren te doen slinken en stopt de groei van de tumoren. Het verschil tussen de groep muizen die het bosbessenpoeder kregen en de controlegroep was significant veel beter voor de bosbessengroep. 70% minder muizen uit de bosbessengroep ontwikkelden leveruitzaaiingen en 25% minder uitzaaiingen naar de lymfklieren. Hier het abstract maar als u hier klikt kunt u het volledige studierapport lezen met tabellen en statistieken.

J Nutr. 2011 Oct;141(10):1805-12. Epub 2011 Aug 31.

Whole Blueberry Powder Modulates the Growth and Metastasis of MDA-MB-231 Triple Negative Breast Tumors in Nude Mice.

Adams LS, Kanaya N, Phung S, Liu Z, Chen S.

Source

Division of Tumor Cell Biology, Beckman Research Institute of the City of Hope, Duarte, CA.

Abstract

Previous studies in our laboratory demonstrated that blueberry (BB) extract exhibited antitumor activity against MDA-MB-231 triple negative breast cancer (TNBC) cells and decreased metastatic potential in vitro. The current study tested 2 doses of whole BB powder, 5 and 10% (wt:wt) in the diet, against MDA-MB-231 tumor growth in female nude mice. In this study, tumor volume was 75% lower in mice fed the 5% BB diet and 60% lower in mice fed the 10% BB diet than in control mice (P ≤ 0.05). Tumor cell proliferation (Ki-67) was lower in the 5 and 10% BB-fed mice and cell death (Caspase 3) was greater in the 10% BB-fed mice compared to control mice (P ≤ 0.05). Gene analysis of tumor tissues from the 5% BB-fed mice revealed significantly altered expression of genes important to inflammation, cancer, and metastasis, specifically, Wnt signaling, thrombospondin-2, IL-13, and IFNγ. To confirm effects on Wnt signaling, analysis of tumor tissues from 5% BB-fed mice revealed lower β-catenin expression and glycogen synthase kinase-3β phosphorylation with greater expression of the β-catenin inhibitory protein adenomatous polyposis coli compared to controls. A second study tested the ability of the 5% BB diet to inhibit MDA-MB-231-luc-D3H2LN metastasis in vivo. In this study, 5% BB-fed mice developed 70% fewer liver metastases (P = 0.04) and 25% fewer lymph node metastases (P = 0.09) compared to control mice. This study demonstrates the oral antitumor and metastasis activity of whole BB powder against TNBC in mice.

PMID:: 21880954; [PubMed - in process]
PMCID: PMC3174855: [Available on 2012/10/1]

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bosbessen, borstkanker

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2 Reacties op "Bosbessen extract doet agressieve borstkankertumoren slinken en stopt groei, blijkt uit dierstudies"

j. timmers :
17/10/2014
Waar en onder welke naam is deze bosbessenpoeder te verkrijgen

Comment
- kees :
  06/08/2015
  Google op bosbessen extract en je krijgt tientallen hits van leveranciers. Het extract van Life extension schijnt wel goed te zijn heb ik wel eens gehoord. Maar ik heb er zelf geen ervaring mee. Maar overleg anders met je begeleidende complementair werkende arts? Die zullen wel weten waar de beste kwaliteit te koop is lijkt mij?
  
  Kees
  
  Comment