11 juni 2023: Bron:  2023 Mar 2. Online ahead of print.

Slechts 500 mg 2x per dag spirulina innemen gedurende 12 weken heeft opmerkelijk groot effect op de cognitieve functie en de metabole parameters - stofwisselingswaarden die bepalend zijn voor het ontstaan en de progressie van de ziekte van Alzheimer zoals hooggevoelige C-reactieve proteïne (hs-CRP) dat ontstekingen in je lichaam aangeeft en nuchtere glucose waarde - bloedsuikerwaarde en insulineweerstand.

Dat blijkt uit een gerandomiseerde studie bij totaal 60 mensen met aangetoonde ziekte van Alzheimer .

Hier een vertaling van het abstract:
Deze studie was gericht op het bepalen van de effecten van de inname van spirulina op de cognitieve functie en de metabole status bij patiënten met de ziekte van Alzheimer. Deze gerandomiseerde, dubbelblinde, gecontroleerde klinische studie werd uitgevoerd onder 60 proefpersonen met de ziekte van Alzheimer. Patiënten werden willekeurig toegewezen om gedurende 12 weken tweemaal daags 500 mg spirulina of een placebo (elk n = 30) te krijgen.

Mini-mental state examination score (MMSE) werd geregistreerd bij alle patiënten voor en na de interventie. Bloedmonsters werden verkregen bij baseline en na 12 weken interventie om metabole markers te bepalen.

  • Vergeleken met placebo resulteerde de inname van spirulina in een significante verbetering van de MMSE-score (spirulinagroep: +0,30 ± 0,99 vs. Placebogroep: respectievelijk -0,38 ± 1,06, p = 0,01).
  • Bovendien verminderde de inname van spirulina het hooggevoelige C-reactieve proteïne (hs-CRP) (spirulina-groep: -0,17 ± 0,29 vs. Placebo-groep: +0,05 ± 0,27 mg/L, p = 0,006),
  • nuchtere glucose (spirulina-groep: -4,56 ± 7,93 vs. placebogroep: +0,80 ± 2,95 mg/dl, p = 0,002),
  • insuline (spirulina-groep: -0,37 ± 0,62 vs. placebogroep: +0,12 ± 0,40 μIE/ml, p = 0,001) en insuline weerstand (spirulinagroep: -0,08 ± 0,13 vs. placebogroep: 0,03 ± 0,08, p = 0,001), en verhoogde insulinegevoeligheid (spirulinagroep: +0,003 ± 0,005 vs. placebogroep: -0,001 ± 0,003, p = 0,003) vergeleken met de placebo.

Over het algemeen toonde ons onderzoek aan dat de inname van spirulina gedurende 12 weken bij patiënten met AD verbeterde cognitieve functie, glucosehomeostaseparameters en hs-CRP-niveaus.  

Het volledige studierapport is tegen betaling verkrijgbaar. Maar hier het abstract van de studie met daaronder een referentielijst van studies met spirulina:


The current study aimed to determine the effects of spirulina intake on cognitive function and metabolic status among patients with Alzheimer's disease (AD). This randomized, double-blind, controlled clinical trial was done among 60 subjects with AD. Patients were randomly assigned to receive either 500 mg/day spirulina or a placebo (each n = 30) twice a day for 12 weeks. Mini-mental state examination score (MMSE) was recorded in all patients before and after intervention. Blood samples were obtained at baseline and after 12 weeks' intervention to determine metabolic markers. Compared with placebo, spirulina intake resulted in a significant improvement in MMSE score (spirulina group: +0.30 ± 0.99 vs. Placebo group: -0.38 ± 1.06, respectively, p = 0.01). In addition, spirulina intake decreased high-sensitivity C-reactive protein (hs-CRP) (spirulina group: -0.17 ± 0.29 vs. Placebo group: +0.05 ± 0.27 mg/L, p = 0.006), fasting glucose (spirulina group: -4.56 ± 7.93 vs. Placebo group: +0.80 ± 2.95 mg/dL, p = 0.002), insulin (spirulina group: -0.37 ± 0.62 vs. Placebo group: +0.12 ± 0.40 μIU/mL, p = 0.001) and insulin resistance (spirulina group: -0.08 ± 0.13 vs. Placebo group: 0.03 ± 0.08, p = 0.001), and increased insulin sensitivity (spirulina group: +0.003 ± 0.005 vs. Placebo group: -0.001 ± 0.003, p = 0.003) compared with the placebo. Overall, our study showed that spirulina intake for 12 weeks in patients with AD improved cognitive function, glucose homeostasis parameters, and hs-CRP levels.

Keywords: Alzheimer's disease; cognitive function; metabolic status; spirulina.

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Plaats een reactie ...

1 Reactie op "Spirulina heeft opmerkelijk goed effect op klinische en stofwisselingswaarden (metabole parameters) bij de ziekte van Alzheimer"

  • Vos :
    Hallo Kees, betekent dit dan even kort door de bocht als je diabetes hebt dat het heel verstandig is om de spirulina te slikken?
    En eventueel als je rond de 60 bent om het cognitieve gedeelte helder te houden?

    Vr gr
    Mw Vos

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