Mocht u kanker-actueel de moeite waard vinden en ons willen ondersteunen om kanker-actueel online te houden dan kunt u ook via uw lidmaatschapsnummer korting krijgen bij enkele bedrijven.

En raadpleeg ook literatuurlijst niet-toxische middelen en behandelingen specifiek bij borstkanker van arts-bioloog drs. Engelbert Valstar

Zie ook bij fysieke activiteit onder complementair bij borstkanker

19 september 2018: Bron: . 2018; 2018: 4783710. Published online 2018 Jul 12

Vrouwen die overgewicht hebben en daarbij ook weinig bewegen en sporten lopen veel groter risico op het krijgen van borstkanker dan vrouwen die veel fysiek actief zijn met veel bewegen en sporten. Die laatste groep lijkt 49 procent minder risico te lopen op het ontwikkelen van borstkanker. Dit blijkt uit een zogeheten case control studie waarbij 116 vrouwen met de eerste diagnose van borstkanker werden vergeleken met 220 vrouwen in een controlegroep. 

De conclusie van de onderzoekers was vrij vertaald dat een lage fysieke activiteit en overgewicht (BMI) bij vrouwen voor de overgang geassocieerd waren met een hoger risico op het krijgen van borstkanker. Echter bij vrouwen na de overgang blijkt alleen fysieke activiteit dat verschil te geven en niet het overgewicht (BMI). De algemene consclusie was wel dat een hoge mate van fysieke activiteit het risico op het krijgen van met borstkanker sterk kan verminderen bij zowel vrouwen voor als vrouwen na de overgang.  

Deze grafiek geeft de studieresultaten weer met ook de verschillen tussen vrouwen van voor en na de overgang:

Table 2

Differences in body composition and level of physical activity between cases and controls according to menopausal status.

PremenopausalPostmenopausal
VariablesCases
(n = 45)
Controls
(n = 88)
p¹Cases
(n = 71)
Controls
(n = 138)
p¹
Body weight (kg) 70.0 ± 13.6 69.4 ± 12.9 0.956 67.9 ± 12.0 68.5 ± 12.7 0.636
Height (m) 1.6 ± 0.06 1.6 ± 0.06 1.000 1.6 ± 0.05 1.6 ± 0.06 0.261
BMI (kg/m2) 28.1 ± 5.2 27.7 ± 5.3 0.618 28.5 ± 5.2 28.3 ± 4.7 0.759
Waist circumference (cm) 91.9 ± 12.4 87.4 ± 13.2 0.058 93.1 ± 11.2 92.2 ± 11.9 0.780
Waist–height ratio 0.57 ± 0.08 0.55 ± 0.09 0.092 0.60 ± 0.07 0.58 ± 0.07 0.515
Conicity index 1.5 ± 0.11 1.4 ± 0.12 0.003 1.5 ± 0.10 1.5 ± 0.10 0.131
Body fat (%) 45.7 ± 6.5 44.0 ± 6.7 0.103 45.2 ± 6.5 45.9 ± 6.1 0.322
Body lean mass (kg) 36.2 ± 5.9 37.4 ± 6.7 0.070 35.4 ± 4.2 35.2 ± 5.2 0.326
Android fat (%) 48.6 ± 8.2 46.3 ± 9.1 0.111 49.9 ± 6.8 50.4 ± 7.1 0.381
Gynoid fat (%) 52.3 ± 5.8 51.5 ± 5.1 0.338 50.9 ± 5.7 52.1 ± 5.4 0.170
Android–gynoid fat ratio 0.92 ± 0.11 0.89 ± 0.15 0.200 0.98 ± 0.10 0.96 ± 0.10 0.498
MET (min/week) 1120 ± 2274 1754 ± 2348 <0.001 1227 ± 1662 1605 ± 2614 0.157

Nonparametric variables (Shapiro-Wilk test).

p < 0.01 controls vs. cases (Mann–Whitney U test).

In het volledige studierapport: Abdominal Adiposity and Physical Inactivity Are Positively Associated with Breast Cancer: A Case-Control Study  dat gratis is in te zien staan nog meer grafieken en gedetailleerde omschrijving van de studie.

Hier het abstract van de studie plus referentielijst.

A low percentage of lean body mass and high abdominal adiposity in the premenopausal period increase the chances of developing breast cancer. Regular physical activity is inversely associated with breast cancer in pre- and postmenopausal women.

. 2018; 2018: 4783710.
Published online 2018 Jul 12. doi:  10.1155/2018/4783710
PMCID: PMC6077523
PMID: 30112392

Abdominal Adiposity and Physical Inactivity Are Positively Associated with Breast Cancer: A Case-Control Study

Abstract

Objective

To examine whether breast cancer is associated with body composition and level of physical activity, considering the menstrual status.

Methods

This was a case-control study with 116 women recently diagnosed with breast cancer and 226 controls. Body composition was assessed by dual-energy X-ray absorptiometry, and cardiometabolic risk was assessed by conicity index and waist-to-height ratio. The short version of the International Physical Activity Questionnaire was used to estimate the level of physical activity. All analyses were adjusted for age and BMI.

Results

The total body fat percentage, android body fat, android-gynoid ratio, and waist circumference were positively associated (p < 0.05), whereas the percentage of lean body mass (p <0.05) and the level of physical activity (p < 0.01) were inversely associated with breast cancer in premenopausal women. Among postmenopausal women, physical activity decreased the chance of developing breast cancer by 49% (95% CI = 0.29 to 0.92, p = 0.02).

Conclusion

A low percentage of lean body mass and high abdominal adiposity in the premenopausal period increase the chances of developing breast cancer. Regular physical activity is inversely associated with breast cancer in pre- and postmenopausal women.

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Articles from BioMed Research International are provided here courtesy of Hindawi Limited

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