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Zie ook dit artikel: 

https://kanker-actueel.nl/vitamine-d-tekort-komt-veel-voor-bij-patienten-besmet-met-het-coronavirus-covid-19-en-vitamine-d-tekort-geeft-veel-groter-risico-meer-dan-50-procent-op-ernstige-klachten-en-overlijden.html

7 januari 2021: Ton geeft de link naar deze studie onderaan dit artikel in een reactie, maar plaats deze ook hier bovenaan dit artikel: 

Over 100 Scientists, Doctors, & Leading Authorities Call For Increased Vitamin D Use To Combat COVID-19

Scientific evidence indicates vitamin D reduces infections & deaths


27 december 2020: Bron: Algemeen Dagblad o.a.

We zouden allemaal vitamine D moeten slikken tegen het coronavirus - Covid-19. Een groep immunologen, wetenschappers en artsen zegt in het Algemeen Dagblad dat er voldoende bewijs is dat vitamine D heel goed beschermt tegen het coronavirus - Covid-19. Afgelopen jaar zijn verschillende grote studies verschenen die aantonen dat mensen met een zogeheten insufficientie = tekort aan vitamine D in het bloed veel hoger risico hebben om besmet te raken met het coronavirus - Covid-19, ook groter risico hebben om in het ziekenhuis en op de IC te belanden en ook een groter risico op overlijden hebben.

Deze groep van wetenschappers en artsen is kwaad op de Nederlandse regering dat zij geen adviezen uit laten gaan om extra vitamine D te gebruiken. 

Citaat uit het artikel in het Algemeen Dagblad: 

Experts boos over uitblijven vitamine D-advies: ‘Alsof het niks interesseert dat mensen dood gaan’

Bijna twee maanden geleden riepen experts in deze krant iedereen op om vitamine D te gaan slikken tegen corona. Deze groep experts kreeg veel bijval van onder meer huisartsen, longartsen en andere hoogleraren. Zo zegt de vooraanstaande hoogleraar voeding en gezondheid Jaap Seidell van de Vrije Universiteit: ,,Wachten op absoluut bewijs bij vitamine D lijkt onverstandig gezien het grote aantal mensen met lage vitamine D spiegels en de belangrijke rol die vitamine D speelt in het immuunsysteem.’’ Hij is - in lijn met onder meer dit wetenschappelijke artikel uit The Lancet - voor het uit voorzorg slikken van vitamine D. 

Zo zegt bv ook Hoogleraar immunologie van de Wageningen Universiteit Huub Savelkoul tegen het Algemeen Dagblad: “Er zijn steeds meer studies die het voordeel van vitamine D aantonen. Ik vind het een soort van arrogantie dat de overheid eerst een metastudie wil afwachten. Het lijkt wel alsof het ons niks interesseert dat er ondertussen mensen in het ziekenhuis komen en dood gaan. Met die opmerking moet u maar voorzichtig zijn, maar dat is wel waar mijn frustratie zit.”

Ook op de website van de WHO worden verschillende stuidies met vitamine D bij ademshalingsproblemen enz. vermeld: 

Vitamin D for prevention of respiratory tract infections

In Nuftrients verscheen afgelopen zomer dit studierapport van prof. dr. Brenner, de Duitse arts die ook door de groep wetenschappers en artsen wordt genoemd in het Algemeen Dagblad. Zie dit citaat:

Hoogleraar Gezond Ouder worden Manfred Eggersdorfer van het Universitair Medisch Centrum Groningen (UMCG) wijst op een studie van de vooraanstaande Duitse kankeronderzoeker Herman Brenner: ,,Daarin staat dat vitamine D-tekorten verantwoordelijk kunnen zijn voor bijna negen van de tien coronadoden. Dat is een geweldig groot aantal!’’ 

Vitamin D Insufficiency and Deficiency and Mortality from Respiratory Diseases in a Cohort of Older Adults: Potential for Limiting the Death Toll during and beyond the COVID-19 Pandemic?

Abstract

The COVID-19 pandemic goes along with increased mortality from acute respiratory disease. It has been suggested that vitamin D3 supplementation might help to reduce respiratory disease mortality. We assessed the prevalence of vitamin D insufficiency and deficiency, defined by 25-hydroxyvitamin D (25(OH)D) blood levels of 30–50 and <30 nmol/L, respectively, and their association with mortality from respiratory diseases during 15 years of follow-up in a cohort of 9548 adults aged 50–75 years from Saarland, Germany. Vitamin D insufficiency and deficiency were common (44% and 15%, respectively). Compared to those with sufficient vitamin D status, participants with vitamin D insufficiency and deficiency had strongly increased respiratory mortality, with adjusted hazard ratios (95% confidence intervals) of 2.1 (1.3–3.2) and 3.0 (1.8–5.2) overall, 4.3 (1.3–14.4) and 8.5 (2.4–30.1) among women, and 1.9 (1.1–3.2) and 2.3 (1.1–4.4) among men. Overall, 41% (95% confidence interval: 20–58%) of respiratory disease mortality was statistically attributable to vitamin D insufficiency or deficiency. Vitamin D insufficiency and deficiency are common and account for a large proportion of respiratory disease mortality in older adults, supporting the hypothesis that vitamin D3

5. Conclusions

In conclusion, our results, along with evidence from meta-analyses from RCTs regarding results of vitamin D3 supplementation on various outcomes, suggest that vitamin D3 supplementation could contribute to lowering mortality from respiratory and other diseases during and beyond the COVID-19 pandemic, in particular among women. The Endocrine Society recommends 1500–2000 IU vitamin D3/day for adults of any age at high risk for vitamin D deficiency []. The costs for such supplementation are in the order of 30 € per person per year, or even half that amount when sufficient vitamin D supply is ensured by carefully dosed sun exposure during the summer months. Along with expected savings from prevented respiratory and other diseases, this would make vitamin D3 supplementation a particularly cost-effective and most likely cost-saving measure, whose currently still widely neglected potential should receive increased attention in the debate on how to fight against the COVID-19 pandemic.

Author Contributions

H.B. designed the research and drafted the manuscript, B.S. conducted statistical analyses, and B.H. critically read and commented the manuscript and added aspects to the discussion. All authors contributed to the data collection for this project. All authors have read and agreed to the published version of the manuscript.

Funding

The ESTHER study was funded by grants from the Saarland state Ministry for Social Affairs, Health, Women and Family Affairs (Saarbrücken, Germany), the Baden-Württemberg state Ministry of Science, Research and Arts (Stuttgart, Germany), the Federal Ministry of Education and Research (Berlin, Germany) and the Federal Ministry of Family Affairs, Senior Citizens, Women and Youth (Berlin, Germany).

Conflicts of Interest

The authors declare no conflict of interest.

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Articles from Nutrients are provided here courtesy of Multidisciplinary Digital Publishing Institute (MDPI)

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Op de website van de WHO staan ook deze referenties:

References

1. WHO. Respiratory tract diseases. Geneva: World Health Organization; 2016. (http://www.who.int/topics/respiratory_tract_diseases/en/)

2. WHO. Pneumonia. Geneva: World Health Organization; 2016. (http://www.who.int/mediacentre/factsheets/fs331/en/)

3. Jiang X, Sun L, Wang B, Yang X, Shang L, Zhang Y. Health-related quality of life among children with recurrent respiratory tract infections in Xi'an, China. PLoS One. 2013;8(2):e56945.

4. Palacios C, Gonzalez L. Is vitamin D deficiency a major global public health problem? Journal of Steroid Biochemistry & Molecular Biology. 2014;144(2014):138-145.

5. Wahl DA, Cooper C, Ebeling PR, Eggersdorfer M, Hilger J, Hoffmann K, Josse R et al.. A global representation of vitamin D status in healthy populations. Archives of Osteoporosis. 2012;7(1):155–172.

6. Greiller CL, Martineau AR. Modulation of the immune response to respiratory viruses by vitamin D. Nutrients. 2015;7(6):4240-70.

7. Wang TT, Dabbas B, Laperriere D, Bitton AJ, Soualhine H, Tavera-Mendoza LE, et al. Direct and indirect induction by 1,25-dihydroxyvitamin D3 of the NOD2/CARD15-defensin beta2 innate immune pathway defective in Crohn disease. Journal of Biological Chemistry. 2010;285(4):2227-31.

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17. Martineau AR, James WY, Hooper RL, Barnes NC, Jolliffe DA, Greiller CL, et al. Vitamin D3 supplementation in patients with chronic obstructive pulmonary disease (ViDiCO): a multicentre, double-blind, randomised controlled trial. The Lancet Respiratory Medicine. 2015;3(2):120-30.

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Disclaimer

The named authors alone are responsible for the views expressed in this document.

Declarations of interests

Conflict of interest statements were collected from all named authors and no conflicts were identified.


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